Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3137974..3138698 Replicon chromosome
Accession NZ_CP007744
Organism Pectobacterium atrosepticum strain JG10-08

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag EV46_RS13675 Protein ID WP_039291161.1
Coordinates 3137974..3138294 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag EV46_RS13680 Protein ID WP_039291159.1
Coordinates 3138363..3138698 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EV46_RS13650 3133486..3133704 + 219 WP_011094380.1 KTSC domain-containing protein -
EV46_RS13655 3134048..3134995 - 948 WP_043135208.1 LysR family transcriptional regulator -
EV46_RS13660 3135107..3136135 + 1029 WP_011094382.1 subclass B3 metallo-beta-lactamase CAR-1 -
EV46_RS13665 3136694..3136891 - 198 WP_051122287.1 hypothetical protein -
EV46_RS13670 3137023..3137856 - 834 WP_039294889.1 DUF4942 domain-containing protein -
EV46_RS13675 3137974..3138294 - 321 WP_039291161.1 TA system toxin CbtA family protein Toxin
EV46_RS13680 3138363..3138698 - 336 WP_039291159.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
EV46_RS13685 3138738..3139211 - 474 WP_039291157.1 DNA repair protein RadC -
EV46_RS13690 3139334..3139684 - 351 WP_039291155.1 hypothetical protein -
EV46_RS13695 3139742..3140575 - 834 WP_039291153.1 hypothetical protein -
EV46_RS23150 3140722..3140880 - 159 WP_155242703.1 hypothetical protein -
EV46_RS13710 3141064..3141951 - 888 WP_039291149.1 50S ribosome-binding GTPase -
EV46_RS13715 3142046..3142972 - 927 WP_039291148.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12022.73 Da        Isoelectric Point: 4.7627

>T46978 WP_039291161.1 NZ_CP007744:c3138294-3137974 [Pectobacterium atrosepticum]
MQTSPAIPPREDNPCPSPITVWQQLLTYLLEKHYGLTLNDTPFCEENVIQAHIDAGVTLVNAVNFLVEKYELVRIDRDGF
NWQEQSPFLTAVDVLRARRATGLLKA

Download         Length: 321 bp

>T46978 NZ_CP007744:c3138294-3137974 [Pectobacterium atrosepticum]
ATGCAAACATCACCTGCAATCCCGCCACGGGAGGATAACCCCTGTCCGTCACCTATAACCGTCTGGCAGCAACTGCTGAC
CTACCTGCTGGAAAAGCACTACGGCCTGACGCTGAACGATACACCATTCTGTGAGGAAAACGTGATTCAAGCGCATATCG
ATGCTGGCGTCACGTTGGTCAATGCCGTGAATTTTCTGGTGGAAAAATACGAACTGGTGCGCATCGATCGCGACGGTTTT
AACTGGCAGGAGCAATCGCCGTTTCTCACTGCCGTTGATGTTCTCCGTGCCAGACGTGCTACCGGCTTGCTCAAAGCATA
A

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12468.28 Da        Isoelectric Point: 6.6874

>AT46978 WP_039291159.1 NZ_CP007744:c3138698-3138363 [Pectobacterium atrosepticum]
MPSSNTPEWGLKCAVTPRFGARLVQEGHRLHYLADRASIVGTFSKTEAQNLERCFPELIKLLEQKLRMGELNPRQQNCVT
LHCNEWICEADTLGSVGYVYIVIYPSSAAAE

Download         Length: 336 bp

>AT46978 NZ_CP007744:c3138698-3138363 [Pectobacterium atrosepticum]
ATGCCATCATCGAATACCCCTGAATGGGGACTAAAATGTGCTGTCACGCCGCGATTCGGAGCCAGGCTGGTTCAGGAAGG
TCACCGCCTGCACTATCTGGCAGACCGGGCCAGCATTGTCGGTACGTTTAGCAAAACAGAAGCCCAAAATCTGGAGCGTT
GCTTCCCTGAGCTAATTAAGCTGTTGGAGCAGAAGCTACGCATGGGGGAACTGAATCCCCGTCAGCAGAACTGCGTCACG
CTGCATTGCAACGAATGGATCTGTGAAGCCGATACGCTGGGCAGTGTTGGCTACGTGTATATTGTTATCTATCCCTCTTC
GGCAGCAGCAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References