Detailed information of TA system TA046977

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 3086320..3087230
• Replicon: chromosome
• Accession: NZ_CP007744
• Organism: Pectobacterium atrosepticum strain JG10-08

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: EV46_RS13440
• Protein ID: WP_039291191.1
• Coordinates: 3086320..3086790 (-)
• Length: 157 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: EV46_RS13445
• Protein ID: WP_039291190.1
• Coordinates: 3086787..3087230 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EV46_RS13420	3081404..3082336	-	933	WP_039291199.1	tRNA dihydrouridine(16) synthase DusC	-
EV46_RS13425	3082580..3083251	+	672	WP_039291197.1	epoxyqueuosine reductase QueH	-
EV46_RS13430	3083298..3084893	-	1596	WP_039291195.1	ABC transporter substrate-binding protein	-
EV46_RS13435	3085034..3086263	+	1230	WP_039291193.1	peptidase T	-
EV46_RS13440	3086320..3086790	-	471	WP_039291191.1	RES family NAD+ phosphorylase	Toxin
EV46_RS13445	3086787..3087230	-	444	WP_039291190.1	DUF2384 domain-containing protein	Antitoxin
EV46_RS23145	3087290..3087403	+	114	Protein_2669	EamA family transporter	-
EV46_RS13450	3087444..3088895	-	1452	WP_039291188.1	ATP-dependent RNA helicase RhlE	-
EV46_RS13455	3089173..3090012	-	840	WP_199559463.1	ABC transporter ATP-binding protein	-
EV46_RS13460	3090040..3091071	-	1032	WP_039291186.1	iron ABC transporter permease	-
EV46_RS13465	3091064..3092053	-	990	WP_039291185.1	iron ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-145)

Antitoxin

• Antitoxin Xre (16-147)

Sequences

Toxin

Protein

• Length: 157 a.a.
• Molecular weight: 17637.08 Da
• Isoelectric Point: 4.4093

>T46977 WP_039291191.1 NZ_CP007744:c3086790-3086320 [Pectobacterium atrosepticum]
MILYRLTKTKYLSTAWTGYGAKEAGGRWNSIGTSMVYVSETASLAMLETLVHLHAAQILDYYTLMRIDVPEDQIQSADMD
ELPDNWAAEEAPPDLAVYGDAWIFTKGSIALRVPSALSPVEYNYLLNPEHPDFYGIIQMAEIIPFQFDSRLKPDRK

Nucleotide

• Length: 471 bp

>T46977 NZ_CP007744:c3086790-3086320 [Pectobacterium atrosepticum]
TTGATTCTCTATCGGCTTACAAAGACAAAGTATCTTTCTACAGCCTGGACGGGATACGGAGCAAAAGAGGCTGGAGGCCG
CTGGAATAGTATTGGCACCTCGATGGTTTATGTATCAGAAACCGCATCGCTTGCCATGCTGGAGACGCTGGTACATCTGC
ATGCAGCGCAGATCCTGGATTATTACACGCTAATGCGTATCGATGTGCCTGAGGATCAGATTCAGAGTGCCGATATGGAC
GAATTGCCAGACAACTGGGCTGCTGAAGAAGCGCCGCCAGATCTGGCTGTATACGGTGATGCATGGATCTTTACCAAAGG
TTCGATAGCGTTGCGAGTCCCCAGCGCCCTATCGCCTGTAGAGTATAACTACCTGTTAAACCCTGAACACCCAGATTTCT
ACGGGATCATTCAGATGGCAGAGATTATACCGTTCCAGTTTGATAGCCGGCTAAAGCCCGATCGTAAATAA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16345.69 Da
• Isoelectric Point: 9.5903

>AT46977 WP_039291190.1 NZ_CP007744:c3087230-3086787 [Pectobacterium atrosepticum]
MKTFSLSTTQTRPPRLWQVAGLNNSDGVALLGQINEGLEGKVANLIADWAKITQNDLRKMSGIPSTTFSRSVKARFSADQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALGGKVPAELMVSETGAYEVMKLLTRLEHGVYS

Nucleotide

• Length: 444 bp

>AT46977 NZ_CP007744:c3087230-3086787 [Pectobacterium atrosepticum]
ATGAAAACATTTAGCTTATCCACGACTCAGACCAGGCCGCCCCGTTTATGGCAGGTGGCCGGATTAAACAATTCTGATGG
TGTGGCGCTTCTGGGACAGATTAACGAAGGCCTTGAGGGCAAGGTTGCTAACCTTATCGCTGACTGGGCGAAGATAACGC
AAAACGACCTGCGTAAAATGTCCGGCATTCCGTCAACGACGTTTAGCCGCAGCGTCAAAGCGCGATTTAGCGCCGATCAA
AGTGAACGGCTGGTGCGTATCATCCGTGTCATTGATCGGGCGGTAGAACTGTTCGAAGGTGATAAGGACGAGGCTCAAAA
ATGGTTGAATGAGCCAAACCGAGCGCTTGGCGGGAAAGTGCCAGCAGAACTGATGGTATCCGAAACCGGGGCTTACGAAG
TCATGAAATTGCTCACGCGCCTGGAACATGGTGTGTACTCTTGA