Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 78913..79448 Replicon chromosome
Accession NZ_CP007744
Organism Pectobacterium atrosepticum strain JG10-08

Toxin (Protein)


Gene name relE Uniprot ID Q6DB38
Locus tag EV46_RS00325 Protein ID WP_011091708.1
Coordinates 78913..79200 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag EV46_RS00330 Protein ID WP_010281712.1
Coordinates 79197..79448 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EV46_RS00305 75045..75866 + 822 WP_011091704.1 energy transducer TonB -
EV46_RS00310 75877..76170 - 294 WP_011091705.1 DUF2623 domain-containing protein -
EV46_RS00315 76486..77328 + 843 WP_011091706.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
EV46_RS00320 77457..78809 + 1353 WP_011091707.1 glutathione-disulfide reductase -
EV46_RS00325 78913..79200 - 288 WP_011091708.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EV46_RS00330 79197..79448 - 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EV46_RS00335 79704..80609 + 906 WP_011091709.1 siderophore-interacting protein -
EV46_RS00340 80644..81399 - 756 WP_011091710.1 thiol:disulfide interchange protein DsbG -
EV46_RS00345 81620..82243 + 624 WP_011091711.1 LysE family translocator -
EV46_RS00350 82290..83162 - 873 WP_011091712.1 LysR family transcriptional regulator -
EV46_RS00355 83262..83774 + 513 WP_161797421.1 phenolic acid decarboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11056.12 Da        Isoelectric Point: 10.3527

>T46971 WP_011091708.1 NZ_CP007744:c79200-78913 [Pectobacterium atrosepticum]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGIKDCYKIKLRASGFRLVYEVIDDVLIIAVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

>T46971 NZ_CP007744:c79200-78913 [Pectobacterium atrosepticum]
ATGAGCTATAGCGTCAAATTCAGGGAAGATGCGCTGAAAGAATGGCTAAAACTCGATAAAACCATCCAACAGCAATTTGC
CAAAAAGCTAAAAAAATGCTGCGAAAACCCTCATATTCCTTCGGCAAAGTTACGGGGGATAAAGGATTGCTACAAAATAA
AGCTCCGGGCGTCAGGCTTTCGCTTAGTGTATGAAGTCATTGACGACGTATTGATTATAGCTGTGGTAGCAGTAGGCAAG
CGTGAACGTAGCGGCGTTTATCATCTGGCAAGTGAGCGAATGAGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT46971 WP_010281712.1 NZ_CP007744:c79448-79197 [Pectobacterium atrosepticum]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp

>AT46971 NZ_CP007744:c79448-79197 [Pectobacterium atrosepticum]
ATGCCGAATATTATATTGAGTGATACCAGTGCCAGCGTCAGTGAACTGAAAAAGAACCCGATGGCAACAGTCAACGCTGG
CGATGGCCTACCTGTCGCTATTCTGAACCGCAACCAGCCTGCGTTTTATTGCATTCCTGCGGATCTCTACGAAAAAATGC
TGGATGCGCTGGACGACCAGGAACTGGTTAAATTGATCGGTGAACGAAAAAACCAGCCGCTGGTTGACGTGGATTTGGAT
AGTTTCCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q6DB38

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References