Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3377263..3377408 Replicon chromosome
Accession NZ_CP007727
Organism Klebsiella pneumoniae subsp. pneumoniae KPNIH10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3377270..3377372 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3377263..3377408 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KPNIH10_RS17080 3372795..3374228 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KPNIH10_RS17085 3374344..3374583 + 240 WP_002911393.1 YebV family protein -
KPNIH10_RS17090 3374681..3374872 + 192 WP_002911395.1 YebW family protein -
KPNIH10_RS17095 3374869..3375522 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
KPNIH10_RS17100 3375679..3376647 + 969 WP_004151446.1 VirK/YbjX family protein -
KPNIH10_RS31545 3376752..3376895 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3377263..3377408 + 146 - - Antitoxin
- 3377270..3377372 - 103 - - Toxin
KPNIH10_RS17110 3377531..3377869 - 339 WP_002911404.1 YebY family protein -
KPNIH10_RS17115 3377886..3378755 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KPNIH10_RS17120 3378759..3379133 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KPNIH10_RS17125 3379246..3379476 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KPNIH10_RS17130 3379555..3380214 + 660 WP_002911407.1 exodeoxyribonuclease X -
KPNIH10_RS17135 3380218..3382278 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T46928 NZ_CP007727:c3377372-3377270 [Klebsiella pneumoniae subsp. pneumoniae KPNIH10]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT46928 NZ_CP007727:3377263-3377408 [Klebsiella pneumoniae subsp. pneumoniae KPNIH10]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References