Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 1140744..1141273 Replicon chromosome
Accession NZ_CP007724
Organism Corynebacterium glutamicum strain AR1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CGLAR1_RS15035 Protein ID WP_080724094.1
Coordinates 1140974..1141273 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag CGLAR1_RS05415 Protein ID WP_038583360.1
Coordinates 1140744..1140977 (+) Length 78 a.a.

Genomic Context

CGLAR1_RS05400CGLAR1_RS05405CGLAR1_RS05410CGLAR1_RS05415CGLAR1_RS15035CGLAR1_RS05420CGLAR1_RS05435CGLAR1_RS15040CGLAR1_RS05450CGLAR1_RS05455CGLAR1_RS05395CGLAR1_RS05425CGLAR1_RS14810CGLAR1_RS05440CGLAR1_RS05445
Location: 1138208..1139293 (1086 bp)
Type: Others
Protein ID: WP_038583350.1
Location: 1139458..1139847 (390 bp)
Type: Others
Protein ID: WP_038583354.1
Location: 1140036..1140476 (441 bp)
Type: Others
Protein ID: WP_038583357.1
Location: 1140744..1140977 (234 bp)
Type: Antitoxin
Protein ID: WP_038583360.1
Location: 1140974..1141273 (300 bp)
Type: Toxin
Protein ID: WP_080724094.1
Location: 1141312..1141578 (267 bp)
Type: Others
Protein ID: WP_143855333.1
Location: 1142943..1143401 (459 bp)
Type: Others
Protein ID: WP_038583364.1
Location: 1143576..1143671 (96 bp)
Type: Others
Protein ID: Protein_1061
Location: 1144832..1145326 (495 bp)
Type: Others
Protein ID: WP_038583369.1
Location: 1145423..1145929 (507 bp)
Type: Others
Protein ID: WP_038586898.1
Location: 1136801..1138012 (1212 bp)
Type: Others
Protein ID: WP_038583347.1
Location: 1141796..1142152 (357 bp)
Type: Others
Protein ID: WP_051904590.1
Location: 1142211..1142723 (513 bp)
Type: Others
Protein ID: WP_145973356.1
Location: 1143787..1144323 (537 bp)
Type: Others
Protein ID: WP_051907073.1
Location: 1144346..1144714 (369 bp)
Type: Others
Protein ID: WP_038583367.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CGLAR1_RS053951136801..1138012-1212WP_038583347.1esterase family protein-
CGLAR1_RS054001138208..1139293+1086WP_038583350.1redox-regulated ATPase YchF-
CGLAR1_RS054051139458..1139847+390WP_038583354.1hypothetical protein-
CGLAR1_RS054101140036..1140476+441WP_038583357.1YtoQ family protein-
CGLAR1_RS054151140744..1140977+234WP_038583360.1type II toxin-antitoxin system ParD family antitoxinAntitoxin
CGLAR1_RS150351140974..1141273+300WP_080724094.1type II toxin-antitoxin system RelE/ParE family toxinToxin
CGLAR1_RS054201141312..1141578+267WP_143855333.1helix-turn-helix transcriptional regulator-
CGLAR1_RS054251141796..1142152-357WP_051904590.1hypothetical protein-
CGLAR1_RS148101142211..1142723-513WP_145973356.1hypothetical protein-
CGLAR1_RS054351142943..1143401+459WP_038583364.1NUDIX domain-containing protein-
CGLAR1_RS150401143576..1143671+96Protein_1061CGNR zinc finger domain-containing protein-
CGLAR1_RS054401143787..1144323-537WP_051907073.1hypothetical protein-
CGLAR1_RS054451144346..1144714-369WP_038583367.1SMI1/KNR4 family protein-
CGLAR1_RS054501144832..1145326+495WP_038583369.12'-5' RNA ligase-
CGLAR1_RS054551145423..1145929+507WP_038586898.1hemerythrin domain-containing protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-74)

Antitoxin

Antitoxin ParD

(1-76)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11462.00 Da        Isoelectric Point: 10.2383

>T46921 WP_080724094.1 NZ_CP007724:1140974-1141273 [Corynebacterium glutamicum]
VSRYLLTPAAQHDLSLIWDFTESRWGISQAKKYIREIQSAVEYVAQDANRGCSREEIRVGYKSTAVGSHVIFYVQRTSHW
KAMKQPVWRPTSARQFVTS

Download         Length: 300 bp

>T46921 NZ_CP007724:1140974-1141273 [Corynebacterium glutamicum]
GTGAGCAGGTACCTTCTTACACCGGCTGCACAGCATGATCTCTCCTTGATTTGGGATTTCACCGAGAGTCGTTGGGGTAT
AAGCCAAGCAAAGAAGTATATCCGTGAGATTCAATCAGCAGTGGAATATGTGGCACAAGATGCGAACCGTGGCTGTAGTC
GTGAGGAAATTCGCGTAGGTTATAAAAGCACTGCGGTAGGCAGCCATGTCATATTTTATGTCCAGCGCACGAGCCATTGG
AAGGCAATGAAACAGCCTGTCTGGAGACCGACATCGGCCAGGCAGTTCGTGACCTCATAG

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8474.45 Da        Isoelectric Point: 4.4143

>AT46921 WP_038583360.1 NZ_CP007724:1140744-1140977 [Corynebacterium glutamicum]
MAMNTSISLDDHFASFLSEQVESGRYQTASEVIRAGLRLLEEREARLTALRAALVNGKMSGEAEEFDFDAFIASKSS

Download         Length: 234 bp

>AT46921 NZ_CP007724:1140744-1140977 [Corynebacterium glutamicum]
ATGGCCATGAATACTTCCATCAGTCTTGATGATCATTTCGCTTCGTTCCTCAGTGAGCAGGTTGAATCCGGTCGGTACCA
GACAGCGAGTGAGGTCATCCGTGCAGGTCTGCGCTTGTTGGAGGAGCGGGAAGCTCGTCTAACTGCTTTACGTGCGGCGC
TTGTAAATGGAAAGATGAGTGGTGAGGCAGAAGAATTTGATTTTGATGCCTTTATCGCATCGAAAAGCTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References