46905

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 719665..720224 Replicon chromosome
Accession NZ_CP007693
Organism Brucella suis bv.

Toxin (Protein)


Gene name brnT Uniprot ID D6LP74
Locus tag BSPT2_RS03385 Protein ID WP_004688321.1
Coordinates 719665..719910 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID Q57DF1
Locus tag BSPT2_RS03390 Protein ID WP_002964097.1
Coordinates 719910..720224 (+) Length 105 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSPT2_RS03360 715512..717158 - 1647 WP_006072703.1 hypothetical protein -
BSPT2_RS03365 717293..718066 - 774 WP_006072701.1 hypothetical protein -
BSPT2_RS03380 718894..719532 - 639 Protein_664 tRNA-guanine transglycosylase -
BSPT2_RS03385 719665..719910 + 246 WP_004688321.1 BrnT family toxin Toxin
BSPT2_RS03390 719910..720224 + 315 WP_002964097.1 BrnA antitoxin family protein Antitoxin
BSPT2_RS03395 720572..720742 + 171 WP_002964095.1 DUF1508 domain-containing protein -
BSPT2_RS03400 721090..721800 - 711 WP_004683739.1 porin family protein -
BSPT2_RS03405 722035..722622 - 588 WP_004683738.1 hypothetical protein -
BSPT2_RS03410 722645..722920 - 276 WP_002964092.1 hypothetical protein -
BSPT2_RS03415 722917..723147 - 231 WP_002964091.1 hypothetical protein -
BSPT2_RS03420 723144..723863 - 720 WP_006072696.1 hypothetical protein -
BSPT2_RS03425 723913..724116 + 204 WP_002964088.1 hypothetical protein -
BSPT2_RS03430 724113..724328 + 216 WP_002971459.1 hypothetical protein -
BSPT2_RS03435 724331..724534 + 204 WP_004690812.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - wbdA / wboA 712398..726318 13920


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 82 a.a.        Molecular weight: 9172.86 Da        Isoelectric Point: 10.3158

>T46905 WP_004688321.1 NZ_CP007693:719665-719910 [Brucella suis bv. 2]
MKIIWDEPKRQTNIAKHGLDFADLHFEFFLSAKVFPTKADRLMAIGEFNGLIIIAVIFKPVGSEALSVISMRPASQKERK
L

Download         Length: 246 bp

>T46905 NZ_CP007693:719665-719910 [Brucella suis bv. 2]
ATGAAGATCATCTGGGACGAACCGAAGCGACAGACCAACATTGCCAAGCACGGCTTGGACTTCGCTGACCTGCATTTCGA
ATTCTTCCTGTCGGCTAAGGTCTTCCCCACCAAGGCAGATCGCCTGATGGCAATCGGAGAATTCAACGGCCTGATTATCA
TCGCCGTCATTTTCAAGCCGGTTGGTTCGGAAGCCCTCTCCGTGATCTCCATGCGTCCAGCAAGCCAGAAGGAAAGGAAG
CTCTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11638.42 Da        Isoelectric Point: 10.3131

>AT46905 WP_002964097.1 NZ_CP007693:719910-720224 [Brucella suis bv. 2]
MGIKFSSKRPLTQEEEAEIQKMIASDPDAPEATDEQLAKAKPFKEAFPDMAAKMEKAIRGRPRIDNPKTPVTIRLDQDVV
QRFKATGKGWQGRMNDALRKAVGL

Download         Length: 315 bp

>AT46905 NZ_CP007693:719910-720224 [Brucella suis bv. 2]
ATGGGTATCAAATTTTCCTCTAAGCGCCCTCTCACTCAGGAAGAAGAGGCAGAAATTCAGAAGATGATCGCAAGCGATCC
CGATGCACCGGAAGCCACCGATGAACAGCTTGCCAAGGCCAAGCCTTTCAAGGAAGCCTTTCCAGATATGGCCGCCAAGA
TGGAGAAGGCCATTCGAGGCCGGCCGCGCATCGACAATCCCAAGACGCCGGTTACTATCCGGCTCGATCAGGATGTAGTT
CAACGCTTCAAGGCCACCGGCAAAGGCTGGCAGGGCCGTATGAACGATGCCCTGCGCAAAGCTGTCGGGCTTTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References