Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | BrnTA/BrnT-BrnA |
Location | 719665..720224 | Replicon | chromosome |
Accession | NZ_CP007693 | ||
Organism | Brucella suis bv. |
Toxin (Protein)
Gene name | brnT | Uniprot ID | D6LP74 |
Locus tag | BSPT2_RS03385 | Protein ID | WP_004688321.1 |
Coordinates | 719665..719910 (+) | Length | 82 a.a. |
Antitoxin (Protein)
Gene name | brnA | Uniprot ID | Q57DF1 |
Locus tag | BSPT2_RS03390 | Protein ID | WP_002964097.1 |
Coordinates | 719910..720224 (+) | Length | 105 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BSPT2_RS03360 | 715512..717158 | - | 1647 | WP_006072703.1 | hypothetical protein | - |
BSPT2_RS03365 | 717293..718066 | - | 774 | WP_006072701.1 | hypothetical protein | - |
BSPT2_RS03380 | 718894..719532 | - | 639 | Protein_664 | tRNA-guanine transglycosylase | - |
BSPT2_RS03385 | 719665..719910 | + | 246 | WP_004688321.1 | BrnT family toxin | Toxin |
BSPT2_RS03390 | 719910..720224 | + | 315 | WP_002964097.1 | BrnA antitoxin family protein | Antitoxin |
BSPT2_RS03395 | 720572..720742 | + | 171 | WP_002964095.1 | DUF1508 domain-containing protein | - |
BSPT2_RS03400 | 721090..721800 | - | 711 | WP_004683739.1 | porin family protein | - |
BSPT2_RS03405 | 722035..722622 | - | 588 | WP_004683738.1 | hypothetical protein | - |
BSPT2_RS03410 | 722645..722920 | - | 276 | WP_002964092.1 | hypothetical protein | - |
BSPT2_RS03415 | 722917..723147 | - | 231 | WP_002964091.1 | hypothetical protein | - |
BSPT2_RS03420 | 723144..723863 | - | 720 | WP_006072696.1 | hypothetical protein | - |
BSPT2_RS03425 | 723913..724116 | + | 204 | WP_002964088.1 | hypothetical protein | - |
BSPT2_RS03430 | 724113..724328 | + | 216 | WP_002971459.1 | hypothetical protein | - |
BSPT2_RS03435 | 724331..724534 | + | 204 | WP_004690812.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | wbdA / wboA | 712398..726318 | 13920 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 82 a.a. Molecular weight: 9172.86 Da Isoelectric Point: 10.3158
>T46905 WP_004688321.1 NZ_CP007693:719665-719910 [Brucella suis bv. 2]
MKIIWDEPKRQTNIAKHGLDFADLHFEFFLSAKVFPTKADRLMAIGEFNGLIIIAVIFKPVGSEALSVISMRPASQKERK
L
MKIIWDEPKRQTNIAKHGLDFADLHFEFFLSAKVFPTKADRLMAIGEFNGLIIIAVIFKPVGSEALSVISMRPASQKERK
L
Download Length: 246 bp
>T46905 NZ_CP007693:719665-719910 [Brucella suis bv. 2]
ATGAAGATCATCTGGGACGAACCGAAGCGACAGACCAACATTGCCAAGCACGGCTTGGACTTCGCTGACCTGCATTTCGA
ATTCTTCCTGTCGGCTAAGGTCTTCCCCACCAAGGCAGATCGCCTGATGGCAATCGGAGAATTCAACGGCCTGATTATCA
TCGCCGTCATTTTCAAGCCGGTTGGTTCGGAAGCCCTCTCCGTGATCTCCATGCGTCCAGCAAGCCAGAAGGAAAGGAAG
CTCTGA
ATGAAGATCATCTGGGACGAACCGAAGCGACAGACCAACATTGCCAAGCACGGCTTGGACTTCGCTGACCTGCATTTCGA
ATTCTTCCTGTCGGCTAAGGTCTTCCCCACCAAGGCAGATCGCCTGATGGCAATCGGAGAATTCAACGGCCTGATTATCA
TCGCCGTCATTTTCAAGCCGGTTGGTTCGGAAGCCCTCTCCGTGATCTCCATGCGTCCAGCAAGCCAGAAGGAAAGGAAG
CTCTGA
Antitoxin
Download Length: 105 a.a. Molecular weight: 11638.42 Da Isoelectric Point: 10.3131
>AT46905 WP_002964097.1 NZ_CP007693:719910-720224 [Brucella suis bv. 2]
MGIKFSSKRPLTQEEEAEIQKMIASDPDAPEATDEQLAKAKPFKEAFPDMAAKMEKAIRGRPRIDNPKTPVTIRLDQDVV
QRFKATGKGWQGRMNDALRKAVGL
MGIKFSSKRPLTQEEEAEIQKMIASDPDAPEATDEQLAKAKPFKEAFPDMAAKMEKAIRGRPRIDNPKTPVTIRLDQDVV
QRFKATGKGWQGRMNDALRKAVGL
Download Length: 315 bp
>AT46905 NZ_CP007693:719910-720224 [Brucella suis bv. 2]
ATGGGTATCAAATTTTCCTCTAAGCGCCCTCTCACTCAGGAAGAAGAGGCAGAAATTCAGAAGATGATCGCAAGCGATCC
CGATGCACCGGAAGCCACCGATGAACAGCTTGCCAAGGCCAAGCCTTTCAAGGAAGCCTTTCCAGATATGGCCGCCAAGA
TGGAGAAGGCCATTCGAGGCCGGCCGCGCATCGACAATCCCAAGACGCCGGTTACTATCCGGCTCGATCAGGATGTAGTT
CAACGCTTCAAGGCCACCGGCAAAGGCTGGCAGGGCCGTATGAACGATGCCCTGCGCAAAGCTGTCGGGCTTTGA
ATGGGTATCAAATTTTCCTCTAAGCGCCCTCTCACTCAGGAAGAAGAGGCAGAAATTCAGAAGATGATCGCAAGCGATCC
CGATGCACCGGAAGCCACCGATGAACAGCTTGCCAAGGCCAAGCCTTTCAAGGAAGCCTTTCCAGATATGGCCGCCAAGA
TGGAGAAGGCCATTCGAGGCCGGCCGCGCATCGACAATCCCAAGACGCCGGTTACTATCCGGCTCGATCAGGATGTAGTT
CAACGCTTCAAGGCCACCGGCAAAGGCTGGCAGGGCCGTATGAACGATGCCCTGCGCAAAGCTGTCGGGCTTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|