Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 267097..267764 Replicon plasmid pRetIE4803d
Accession NZ_CP007645
Organism Rhizobium etli bv. phaseoli str. IE4803

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IE4803_RS30795 Protein ID WP_040112759.1
Coordinates 267097..267540 (-) Length 148 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IE4803_RS30800 Protein ID WP_089152845.1
Coordinates 267537..267764 (-) Length 76 a.a.

Genomic Context

IE4803_RS30780IE4803_RS35390IE4803_RS34595IE4803_RS30790IE4803_RS30825IE4803_RS30830IE4803_RS30795IE4803_RS30800IE4803_RS30805IE4803_RS30810IE4803_RS30815IE4803_RS30820
Location: 262909..263226 (318 bp)
Type: Others
Protein ID: Protein_244
Location: 263380..263547 (168 bp)
Type: Others
Protein ID: WP_194252299.1
Location: 263854..264405 (552 bp)
Type: Others
Protein ID: WP_080771826.1
Location: 265482..266977 (1496 bp)
Type: Others
Protein ID: Protein_247
Location: 271275..271814 (540 bp)
Type: Others
Protein ID: WP_010041279.1
Location: 271818..272477 (660 bp)
Type: Others
Protein ID: WP_040112761.1
Location: 267097..267540 (444 bp)
Type: Toxin
Protein ID: WP_040112759.1
Location: 267537..267764 (228 bp)
Type: Antitoxin
Protein ID: WP_089152845.1
Location: 268165..268530 (366 bp)
Type: Others
Protein ID: WP_010040844.1
Location: 268527..269231 (705 bp)
Type: Others
Protein ID: WP_040112760.1
Location: 269228..270214 (987 bp)
Type: Others
Protein ID: WP_040113156.1
Location: 270811..271176 (366 bp)
Type: Others
Protein ID: WP_040113157.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
IE4803_RS30780262909..263226+318Protein_244transposase-
IE4803_RS35390263380..263547+168WP_194252299.1hypothetical protein-
IE4803_RS34595263854..264405+552WP_080771826.1hypothetical protein-
IE4803_RS30790265482..266977+1496Protein_247EAL domain-containing protein-
IE4803_RS30795267097..267540-444WP_040112759.1PIN domain-containing proteinToxin
IE4803_RS30800267537..267764-228WP_089152845.1CopG family transcriptional regulatorAntitoxin
IE4803_RS30805268165..268530-366WP_010040844.1GtrA family protein-
IE4803_RS30810268527..269231-705WP_040112760.1HAD family hydrolase-
IE4803_RS30815269228..270214-987WP_040113156.1UbiA prenyltransferase family protein-
IE4803_RS30820270811..271176-366WP_040113157.1hypothetical protein-
IE4803_RS30825271275..271814+540WP_010041279.1hypothetical protein-
IE4803_RS30830271818..272477+660WP_040112761.1transglycosylase SLT domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideConjugative plasmid--1..742914742914
-flankIS/Tn--262981..263226245


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 148 a.a.        Molecular weight: 15548.86 Da        Isoelectric Point: 9.0576

>T46776 WP_040112759.1 NZ_CP007645:c267540-267097 [Rhizobium etli bv. phaseoli str. IE4803]
VTFLLDVNVLIALIDPGHVAHDDAHAWFAVVGQTAWATCPITENGVIRIVGNPKYPNSPGSPALVMEIVRKLRSLPGHSF
WSDDVSLVGSGNIAPTKILTPGQVTDTYLLALAKARGGQLATFDRKLSAAAVTRGNSALHLITTSRS

Download         Length: 444 bp

>T46776 NZ_CP007645:c267540-267097 [Rhizobium etli bv. phaseoli str. IE4803]
GTGACTTTCCTGCTCGACGTCAATGTGCTGATTGCCTTAATCGATCCGGGACATGTAGCCCATGATGATGCACACGCATG
GTTCGCAGTGGTGGGTCAGACCGCGTGGGCTACCTGCCCCATTACCGAAAATGGTGTCATCCGGATTGTCGGCAACCCCA
AATATCCCAACTCTCCCGGTTCACCGGCACTCGTGATGGAGATCGTCCGCAAATTGCGGTCGCTCCCCGGTCACAGCTTT
TGGTCGGACGATGTGAGCCTTGTGGGGTCAGGTAATATCGCGCCCACGAAAATTCTAACACCGGGACAGGTAACTGATAC
CTACCTGCTTGCGCTAGCCAAGGCGCGTGGTGGCCAGCTGGCGACATTCGATCGCAAGCTTTCAGCGGCAGCGGTTACAA
GGGGCAATTCTGCCTTGCACCTGATCACCACGAGTAGATCGTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8210.47 Da        Isoelectric Point: 7.0120

>AT46776 WP_089152845.1 NZ_CP007645:c267764-267537 [Rhizobium etli bv. phaseoli str. IE4803]
MRTTLAIDDDVLIAAKAMATQQHRSVGEVISELARRSLRRPPSIGERNGIPLLSARPDTPPVTLEIVNALRDELP

Download         Length: 228 bp

>AT46776 NZ_CP007645:c267764-267537 [Rhizobium etli bv. phaseoli str. IE4803]
ATGAGAACGACTTTGGCAATCGACGACGATGTCCTGATCGCCGCAAAGGCGATGGCAACCCAGCAGCACCGGAGCGTCGG
CGAGGTCATTTCTGAGCTGGCGAGACGTTCTCTGCGCCGACCGCCCAGCATCGGTGAACGCAATGGCATTCCTCTCCTGT
CAGCTCGGCCGGATACGCCGCCAGTGACGCTCGAAATCGTGAACGCCTTGCGTGACGAACTGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References