Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2246776..2247047 | Replicon | chromosome |
| Accession | NZ_CP007592 | ||
| Organism | Escherichia coli O157:H16 strain Santai | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2246814..2246917 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2246776..2247047 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CH99_RS10915 | 2243933..2245372 | + | 1440 | WP_024227172.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| CH99_RS10920 | 2245490..2245726 | + | 237 | WP_001295499.1 | DUF1480 family protein | - |
| CH99_RS10925 | 2245831..2246022 | + | 192 | WP_001313035.1 | YebW family protein | - |
| CH99_RS10930 | 2246023..2246679 | - | 657 | WP_021556895.1 | protein-serine/threonine phosphatase | - |
| - | 2246776..2247047 | + | 272 | - | - | Antitoxin |
| - | 2246814..2246917 | - | 104 | - | - | Toxin |
| CH99_RS10940 | 2247075..2247416 | - | 342 | WP_000976472.1 | YebY family protein | - |
| CH99_RS10945 | 2247429..2248301 | - | 873 | WP_000879298.1 | copper homeostasis membrane protein CopD | - |
| CH99_RS10950 | 2248305..2248679 | - | 375 | WP_021556896.1 | CopC domain-containing protein YobA | - |
| CH99_RS10955 | 2248818..2249048 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| CH99_RS10960 | 2249150..2249806 | + | 657 | WP_000011660.1 | carbon-nitrogen hydrolase family protein | - |
| CH99_RS10965 | 2249830..2250492 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T46662 NZ_CP007592:c2246917-2246814 [Escherichia coli O157:H16]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT46662 NZ_CP007592:2246776-2247047 [Escherichia coli O157:H16]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
