46656

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEii-AbiEi
Location 917485..918952 Replicon chromosome
Accession NZ_CP007591
Organism Mycoplasmopsis bovis strain HB0801-P180

Toxin (Protein)


Gene name abiEi Uniprot ID A0A2N8U3K6
Locus tag BC93_RS03885 Protein ID WP_014829995.1
Coordinates 917485..918345 (-) Length 287 a.a.

Antitoxin (Protein)


Gene name abiEii Uniprot ID Q934C3
Locus tag BC93_RS03890 Protein ID WP_013456322.1
Coordinates 918338..918952 (-) Length 205 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BC93_RS04650 913406..913774 - 369 WP_062931873.1 variable surface lipoprotein -
BC93_RS04545 913933..914829 - 897 WP_014829992.1 variable surface lipoprotein -
BC93_RS03875 915529..916275 + 747 WP_231140160.1 variable surface lipoprotein -
BC93_RS04550 916337..916489 + 153 WP_181728443.1 hypothetical protein -
BC93_RS03880 916532..917365 - 834 WP_014829994.1 variable surface lipoprotein -
BC93_RS03885 (BC93_0712) 917485..918345 - 861 WP_014829995.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
BC93_RS03890 (BC93_0714) 918338..918952 - 615 WP_013456322.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
BC93_RS03895 (BC93_0715) 919364..920113 + 750 WP_013456123.1 tyrosine-type recombinase/integrase -
BC93_RS03905 (BC93_0716) 920512..922356 + 1845 WP_013955063.1 ribonuclease J -
BC93_RS03910 (BC93_0717) 922491..923642 + 1152 WP_013955064.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 896454..920113 23659


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-234)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(13-59)


Sequences

Toxin        


Download         Length: 287 a.a.        Molecular weight: 33280.36 Da        Isoelectric Point: 7.7731

>T46656 WP_014829995.1 NZ_CP007591:c918345-917485 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADQNNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND

Download         Length: 861 bp

>T46656 NZ_CP007591:c918345-917485 [Mycoplasmopsis bovis]
ATGAATAAAAATAAATTAATAAGTTTGTGTCATAAAACTGCTGATCAAAATAACGCAAATTTCAATGTTGTTTTAATTCA
ATATTTTATGGAAAGCATTCTACGAAGAATATCTAAAAGTAATGAGAGAGACAATTTTGTGTTCAAGGGCGGTTTTCTTT
TATCTAACATTATGGGGTTAGATAAAAGAGCTACAATGGATATTGATTTGGAGCTAATAAAAACTCAAAAGATAAGTGCT
TCTAAAATATTAGAAAAATTTAAAAGTATATTAAACGCTGATGACATCGATGGAATTAGATATCACATTCTTAAGTATAC
TGACATTCGAAAGGAGCATAAATATAGTGGCATTAACATATCAGTCCTATGTCAAATAGAGAATATAAAACAAGTTATTT
CTATAGATATTGCATCAGGCGATGTCATTACACCTAAGGAAATTGTTTATGAATACAAAAGTATATTTTCAAATCAGGAT
TTTTCTATTTTAGCTTATAACATTGAAACTATGCTATCTGAAAAGCTTGAGACAATATTTTCTTTTGGTCACTTAAATAC
AAGATTTAAAGATTTTTATGATGTTTATGTTATATACACTTTTAAAAAGAAGGACATTGATATTAATAGGCTCAAGGATG
CTTGCTATAACACATTCAAAAATAGGAACAGTGAATTTAACATACAACAATTGTTGGAACTAATTACCAATATTGCTTTC
AATCCGTTGATGAATGAAAGATGAAAAAAGTACATAAGTCAGATAGCAAATCAGCAGGAAATAGACTTTAAAGCCATTAC
TAATTCAATAATAGAACTACTAGAACTAATTAAGGTCAATGAATTAACAAATAATGATTAA

Antitoxin


Download         Length: 205 a.a.        Molecular weight: 24143.83 Da        Isoelectric Point: 9.7617

>AT46656 WP_013456322.1 NZ_CP007591:c918952-918338 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE

Download         Length: 615 bp

>AT46656 NZ_CP007591:c918952-918338 [Mycoplasmopsis bovis]
ATGGAACAAAAAAACTTAAATTCGAAATATTACAATGCAATTTTTAAACTGTTACATAAAAATAACGGTGTTATCACATA
TAAGCAACTAAAAGAAAACAATATATCTTCTATATATTTAACAAGAATGATAACAAAAGGCGTTCTTATTAGAAGAGCTA
AAGGCATTTATATTCTTAGTGATGGACATTACGATGAATATTATTTCTTAAGCAAAAACTATAAATCGTTAATCTTTTCT
CATTATAGTGCACTATATTTAAATAATATTATTGACATTTTTCCGCATCAAATTGACGTTACAGTTTACAGTGGCTATAA
TGCAAAAGGCATTAAGAAGCATGCAAATGTTTACTACTGTGATAGGAATAAACATTCAATTGGACTATCTGAATCAAAAA
CATTATTTGGAAACAAAGTTAAGGTATATGACTTTGAGAGAACAATTTGTGATTTTGTAAAACTACGCAAGAAAACAGAT
AGCGAAATCTTTTCTAAGCTTATTAGTGCATATATTAAATATGAAAATAGAGATTGAAAAAAATTGTATGAATACGCCTA
TGAATTAGGCATACACAAAAAAATATCGGAGATATTTGAACTATTTTATGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2N8U3K6

Antitoxin

Source ID Structure
AlphaFold DB Q934C3

References