Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 4788703..4789469 Replicon chromosome
Accession NZ_CP007410
Organism Pseudomonas brassicacearum strain DF41

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag CD58_RS20280 Protein ID WP_025214811.1
Coordinates 4788981..4789469 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag CD58_RS20275 Protein ID WP_038436701.1
Coordinates 4788703..4788990 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CD58_RS20250 4784818..4785753 + 936 WP_025214805.1 AraC family transcriptional regulator -
CD58_RS20255 4785828..4786301 + 474 WP_025214806.1 GNAT family N-acetyltransferase -
CD58_RS20260 4786319..4786546 - 228 WP_025214807.1 integrase -
CD58_RS20265 4786758..4787579 + 822 WP_025214808.1 DUF1206 domain-containing protein -
CD58_RS20270 4787581..4788072 - 492 WP_025214809.1 nuclear transport factor 2 family protein -
CD58_RS20275 4788703..4788990 + 288 WP_038436701.1 DUF1778 domain-containing protein Antitoxin
CD58_RS20280 4788981..4789469 + 489 WP_025214811.1 hypothetical protein Toxin
CD58_RS20290 4790001..4790690 + 690 WP_025214812.1 crotonase/enoyl-CoA hydratase family protein -
CD58_RS20295 4790906..4791628 + 723 WP_025214813.1 1-acylglycerol-3-phosphate O-acyltransferase -
CD58_RS20300 4791764..4792735 + 972 WP_025214814.1 magnesium and cobalt transport protein CorA -
CD58_RS20305 4792839..4793573 - 735 WP_025214815.1 amidotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4772193..4789469 17276


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(14-90)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17652.37 Da        Isoelectric Point: 8.4743

>T46417 WP_025214811.1 NZ_CP007410:4788981-4789469 [Pseudomonas brassicacearum]
VELRAPEKLNDEHILDEFDSGVASINDYLQRQARKAQAAKQAVVYVICRKDTPVVMGYYTLSSGSIARENVVPKSHQRNS
PSVHPVTLLGRMGVTLAAQGQGFAIDLLQDAIERAITASSTIGSTAMIVHPLTERLSSFYIKYAGFIPCPGLSPITLMLP
LR

Download         Length: 489 bp

>T46417 NZ_CP007410:4788981-4789469 [Pseudomonas brassicacearum]
GTGGAGCTGAGGGCTCCGGAAAAGCTGAACGATGAACACATCCTGGATGAATTCGATTCTGGTGTGGCATCGATCAACGA
TTACCTCCAAAGACAAGCGCGCAAAGCTCAAGCGGCAAAACAGGCCGTTGTATACGTGATCTGTCGAAAGGATACGCCCG
TCGTCATGGGCTATTACACCCTGTCGAGCGGATCGATCGCACGCGAGAACGTCGTTCCGAAAAGCCATCAACGCAACTCT
CCAAGCGTGCATCCGGTGACACTCCTGGGGCGCATGGGGGTCACTCTCGCAGCGCAAGGCCAAGGCTTTGCAATTGACTT
GCTGCAAGATGCGATTGAACGAGCGATTACTGCGTCAAGCACCATCGGCTCTACCGCAATGATTGTTCACCCGCTTACTG
AACGTCTGTCGAGCTTTTACATCAAATACGCCGGGTTTATACCGTGTCCAGGGCTTTCGCCCATTACGCTGATGTTGCCG
CTTCGGTAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10860.63 Da        Isoelectric Point: 7.7214

>AT46417 WP_038436701.1 NZ_CP007410:4788703-4788990 [Pseudomonas brassicacearum]
MTVCIEEKSKPVPINMRADEKKRNLIDLAAAMSGRDRTSFILEAACQKAEEVILNKRLFLLDDAAFDAFEQAMEANPIRG
NKCLHQLLERPKRWS

Download         Length: 288 bp

>AT46417 NZ_CP007410:4788703-4788990 [Pseudomonas brassicacearum]
ATGACCGTATGTATTGAAGAAAAATCCAAGCCCGTGCCCATCAACATGAGAGCGGATGAAAAAAAACGCAACCTGATCGA
TCTGGCGGCTGCTATGTCCGGTCGTGATCGAACCAGCTTTATCTTGGAAGCTGCTTGTCAGAAAGCAGAGGAAGTCATTC
TGAATAAACGGCTGTTCCTTCTCGACGACGCGGCGTTTGACGCATTTGAGCAGGCCATGGAAGCGAATCCAATTCGAGGT
AACAAGTGCCTGCATCAACTTCTCGAAAGGCCCAAACGGTGGAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References