Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2721769..2722037 Replicon chromosome
Accession NZ_CP007393
Organism Escherichia coli strain ST2747

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2721807..2721910 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2721769..2722037 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CF59_RS13120 2718926..2720365 + 1440 WP_025210565.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CF59_RS13125 2720483..2720719 + 237 WP_025210566.1 DUF1480 family protein -
CF59_RS13130 2720824..2721015 + 192 WP_001296140.1 YebW family protein -
CF59_RS13135 2721016..2721672 - 657 WP_025210567.1 protein-serine/threonine phosphatase -
- 2721769..2722037 + 269 - - Antitoxin
- 2721807..2721910 - 104 - - Toxin
CF59_RS13145 2722067..2722408 - 342 WP_000976472.1 YebY family protein -
CF59_RS13150 2722421..2723293 - 873 WP_025210568.1 copper homeostasis membrane protein CopD -
CF59_RS13155 2723297..2723671 - 375 WP_000168745.1 CopC domain-containing protein YobA -
CF59_RS13160 2723810..2724040 + 231 WP_000916763.1 DNA polymerase III subunit theta -
CF59_RS13165 2724142..2724798 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
CF59_RS13170 2724822..2725484 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2705929..2746534 40605


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T46364 NZ_CP007393:c2721910-2721807 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT46364 NZ_CP007393:2721769-2722037 [Escherichia coli]
AAAGTCAGCGAAAGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References