Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2052622..2052890 Replicon chromosome
Accession NZ_CP007391
Organism Escherichia coli strain ST540

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2052749..2052852 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2052622..2052890 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CF61_RS10255 2049344..2050006 - 663 WP_000944256.1 exodeoxyribonuclease X -
CF61_RS10260 2050030..2050686 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
CF61_RS10265 2050788..2050877 - 90 Protein_1936 DNA polymerase III subunit theta -
CF61_RS10270 2050988..2051362 + 375 WP_000168739.1 CopC domain-containing protein YobA -
CF61_RS10275 2051366..2052238 + 873 WP_000879277.1 copper homeostasis membrane protein CopD -
CF61_RS10280 2052251..2052592 + 342 WP_001515445.1 YebY family protein -
- 2052622..2052890 - 269 - - Antitoxin
- 2052749..2052852 + 104 - - Toxin
CF61_RS10290 2052987..2053643 + 657 WP_001515444.1 protein-serine/threonine phosphatase -
CF61_RS10295 2053644..2053835 - 192 WP_001296140.1 YebW family protein -
CF61_RS10300 2053940..2054176 - 237 WP_001295499.1 DUF1480 family protein -
CF61_RS10305 2054294..2055733 - 1440 WP_024189843.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T46300 NZ_CP007391:2052749-2052852 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT46300 NZ_CP007391:c2052890-2052622 [Escherichia coli]
AAAGTCAGCGAAGGGAATGTTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References