Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1010316..1010584 Replicon chromosome
Accession NZ_CP007275
Organism Escherichia coli strain O18

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1010354..1010456 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1010316..1010584 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMECO18_RS05315 1007473..1008912 + 1440 WP_001350670.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NMECO18_RS05320 1009030..1009266 + 237 WP_001295499.1 DUF1480 family protein -
NMECO18_RS05325 1009371..1009562 + 192 WP_001296140.1 YebW family protein -
NMECO18_RS05330 1009563..1010219 - 657 WP_000812741.1 protein-serine/threonine phosphatase -
- 1010316..1010584 + 269 - - Antitoxin
- 1010354..1010456 - 103 - - Toxin
NMECO18_RS05340 1010614..1010955 - 342 WP_000984819.1 YebY family protein -
NMECO18_RS05345 1010968..1011840 - 873 WP_000879320.1 copper homeostasis membrane protein CopD -
NMECO18_RS05350 1011844..1012218 - 375 WP_000168747.1 CopC domain-containing protein YobA -
NMECO18_RS05355 1012357..1012587 + 231 WP_000916763.1 DNA polymerase III subunit theta -
NMECO18_RS05360 1012689..1013345 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
NMECO18_RS05365 1013368..1014030 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T46248 NZ_CP007275:c1010456-1010354 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT46248 NZ_CP007275:1010316-1010584 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References