Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mazEF/MazF(toxin) |
| Location | 183879..184414 | Replicon | plasmid pLRE138 |
| Accession | NZ_CP007257 | ||
| Organism | Rhodococcus erythropolis R138 | ||
Toxin (Protein)
| Gene name | mazF | Uniprot ID | - |
| Locus tag | H351_RS29915 | Protein ID | WP_029256889.1 |
| Coordinates | 183879..184178 (-) | Length | 100 a.a. |
Antitoxin (Protein)
| Gene name | mazE | Uniprot ID | - |
| Locus tag | H351_RS29920 | Protein ID | WP_029256888.1 |
| Coordinates | 184178..184414 (-) | Length | 79 a.a. |
Genomic Context
Location: 179151..180929 (1779 bp)
Type: Others
Protein ID: WP_029256892.1
Type: Others
Protein ID: WP_029256892.1
Location: 181203..182000 (798 bp)
Type: Others
Protein ID: WP_029256891.1
Type: Others
Protein ID: WP_029256891.1
Location: 182000..183850 (1851 bp)
Type: Others
Protein ID: WP_029256890.1
Type: Others
Protein ID: WP_029256890.1
Location: 183879..184178 (300 bp)
Type: Toxin
Protein ID: WP_029256889.1
Type: Toxin
Protein ID: WP_029256889.1
Location: 184178..184414 (237 bp)
Type: Antitoxin
Protein ID: WP_029256888.1
Type: Antitoxin
Protein ID: WP_029256888.1
Location: 184872..185543 (672 bp)
Type: Others
Protein ID: WP_029256886.1
Type: Others
Protein ID: WP_029256886.1
Location: 185605..186579 (975 bp)
Type: Others
Protein ID: WP_029256885.1
Type: Others
Protein ID: WP_029256885.1
Location: 187203..187517 (315 bp)
Type: Others
Protein ID: WP_029256884.1
Type: Others
Protein ID: WP_029256884.1
Location: 187514..188296 (783 bp)
Type: Others
Protein ID: WP_029256883.1
Type: Others
Protein ID: WP_029256883.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H351_RS31715 | 179151..180929 | - | 1779 | WP_029256892.1 | aminodeoxychorismate synthase component I | - |
| H351_RS29905 | 181203..182000 | - | 798 | WP_029256891.1 | hypothetical protein | - |
| H351_RS29910 | 182000..183850 | - | 1851 | WP_029256890.1 | hypothetical protein | - |
| H351_RS29915 | 183879..184178 | - | 300 | WP_029256889.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
| H351_RS29920 | 184178..184414 | - | 237 | WP_029256888.1 | hypothetical protein | Antitoxin |
| H351_RS29930 | 184872..185543 | - | 672 | WP_029256886.1 | TetR/AcrR family transcriptional regulator | - |
| H351_RS29935 | 185605..186579 | - | 975 | WP_029256885.1 | DUF2637 domain-containing protein | - |
| H351_RS29940 | 187203..187517 | - | 315 | WP_029256884.1 | hypothetical protein | - |
| H351_RS29945 | 187514..188296 | - | 783 | WP_029256883.1 | AAA family ATPase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..477915 | 477915 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 100 a.a. Molecular weight: 14735.68 Da Isoelectric Point: 5.5500
>T46211 WP_029256889.1 NZ_CP007257:c184178-183879 [Rhodococcus erythropolis R138]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFF
Download Length: 300 bp
>T46211 NZ_CP007257:c184178-183879 [Rhodococcus erythropolis R138]
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Antitoxin
Download Length: 79 a.a. Molecular weight: 11644.97 Da Isoelectric Point: 5.5500
>AT46211 WP_029256888.1 NZ_CP007257:c184414-184178 [Rhodococcus erythropolis R138]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
Download Length: 237 bp
>AT46211 NZ_CP007257:c184414-184178 [Rhodococcus erythropolis R138]
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