Detailed information of TA system TA046211

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazEF/MazF(toxin)
• Location: 183879..184414
• Replicon: plasmid pLRE138
• Accession: NZ_CP007257
• Organism: Rhodococcus erythropolis R138

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: -
• Locus tag: H351_RS29915
• Protein ID: WP_029256889.1
• Coordinates: 183879..184178 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: -
• Locus tag: H351_RS29920
• Protein ID: WP_029256888.1
• Coordinates: 184178..184414 (-)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H351_RS31715	179151..180929	-	1779	WP_029256892.1	aminodeoxychorismate synthase component I	-
H351_RS29905	181203..182000	-	798	WP_029256891.1	hypothetical protein	-
H351_RS29910	182000..183850	-	1851	WP_029256890.1	hypothetical protein	-
H351_RS29915	183879..184178	-	300	WP_029256889.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
H351_RS29920	184178..184414	-	237	WP_029256888.1	hypothetical protein	Antitoxin
H351_RS29930	184872..185543	-	672	WP_029256886.1	TetR/AcrR family transcriptional regulator	-
H351_RS29935	185605..186579	-	975	WP_029256885.1	DUF2637 domain-containing protein	-
H351_RS29940	187203..187517	-	315	WP_029256884.1	hypothetical protein	-
H351_RS29945	187514..188296	-	783	WP_029256883.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..477915	477915

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 14735.68 Da
• Isoelectric Point: 5.5500

>T46211 WP_029256889.1 NZ_CP007257:c184178-183879 [Rhodococcus erythropolis R138]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 300 bp

>T46211 NZ_CP007257:c184178-183879 [Rhodococcus erythropolis R138]
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Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 11644.97 Da
• Isoelectric Point: 5.5500

>AT46211 WP_029256888.1 NZ_CP007257:c184414-184178 [Rhodococcus erythropolis R138]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 237 bp

>AT46211 NZ_CP007257:c184414-184178 [Rhodococcus erythropolis R138]
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