Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1842186..1842714 Replicon chromosome
Accession NZ_CP007243
Organism Leptospirillum ferriphilum YSK

Toxin (Protein)


Gene name relE Uniprot ID A0A059Y0K5
Locus tag Y981_RS09215 Protein ID WP_038505928.1
Coordinates 1842433..1842714 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag Y981_RS09210 Protein ID WP_203225164.1
Coordinates 1842186..1842446 (+) Length 87 a.a.

Genomic Context

Y981_RS12165Y981_RS09205Y981_RS09210Y981_RS09215Y981_RS09225Y981_RS09180Y981_RS09190Y981_RS12725Y981_RS09220
Location: 1839971..1840489 (519 bp)
Type: Others
Protein ID: WP_158423171.1
Location: 1841390..1841983 (594 bp)
Type: Others
Protein ID: WP_197075622.1
Location: 1842186..1842446 (261 bp)
Type: Antitoxin
Protein ID: WP_203225164.1
Location: 1842433..1842714 (282 bp)
Type: Toxin
Protein ID: WP_038505928.1
Location: 1844066..1846990 (2925 bp)
Type: Others
Protein ID: WP_038505933.1
Location: 1837331..1838593 (1263 bp)
Type: Others
Protein ID: WP_038505919.1
Location: 1838855..1839757 (903 bp)
Type: Others
Protein ID: WP_101494876.1
Location: 1840845..1841210 (366 bp)
Type: Others
Protein ID: Protein_1739
Location: 1843083..1843799 (717 bp)
Type: Others
Protein ID: WP_038505931.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
Y981_RS091801837331..1838593-1263WP_038505919.1NAD-binding protein-
Y981_RS091901838855..1839757-903WP_101494876.1pirin family protein-
Y981_RS121651839971..1840489+519WP_158423171.1Slp family lipoprotein-
Y981_RS127251840845..1841210-366Protein_1739site-specific integrase-
Y981_RS092051841390..1841983+594WP_197075622.1HNH endonuclease family protein-
Y981_RS092101842186..1842446+261WP_203225164.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
Y981_RS092151842433..1842714+282WP_038505928.1type II toxin-antitoxin system YafQ family toxinToxin
Y981_RS092201843083..1843799-717WP_038505931.1hypothetical protein-
Y981_RS092251844066..1846990+2925WP_038505933.1TonB-dependent receptor-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-82)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10587.14 Da        Isoelectric Point: 9.9575

>T46207 WP_038505928.1 NZ_CP007243:1842433-1842714 [Leptospirillum ferriphilum YSK]
MRTIERSSAFKRDFKREIRGKHKATLESDLANVLVLLVQDQPLGAHYRDHDLSGDWGGYRECHIKPDLLLIYRKVDGATL
RLARLGSHSGLFG

Download         Length: 282 bp

>T46207 NZ_CP007243:1842433-1842714 [Leptospirillum ferriphilum YSK]
ATGCGGACGATTGAACGTTCTTCTGCTTTCAAAAGAGACTTTAAGCGAGAAATTAGAGGGAAACATAAAGCGACCCTGGA
GTCTGACCTGGCGAATGTCTTGGTGTTGTTGGTCCAAGACCAGCCACTTGGAGCTCACTACAGGGATCATGACTTGAGCG
GTGATTGGGGCGGCTATCGCGAGTGTCATATCAAACCCGATCTGCTGCTGATCTATCGAAAAGTCGATGGAGCCACCTTG
CGGCTGGCTCGTCTTGGTTCCCATAGTGGGTTATTCGGTTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9627.08 Da        Isoelectric Point: 5.8770

>AT46207 WP_203225164.1 NZ_CP007243:1842186-1842446 [Leptospirillum ferriphilum YSK]
MTGTYVRARIDPGTKERATEALEKMGLSVSDAIRLLMLRIAEEHRMPFEIKVPNATTRKAIKELESGKGERFTTVDSLMA
DMNADD

Download         Length: 261 bp

>AT46207 NZ_CP007243:1842186-1842446 [Leptospirillum ferriphilum YSK]
ATGACAGGAACATATGTTCGCGCCCGGATCGACCCGGGTACCAAAGAACGAGCGACCGAAGCGCTGGAAAAGATGGGGTT
GTCGGTTTCGGATGCGATCCGTCTCCTGATGCTCCGCATTGCGGAAGAGCATCGAATGCCTTTTGAAATCAAGGTTCCGA
ATGCAACGACCCGAAAAGCGATTAAAGAACTTGAAAGCGGAAAGGGAGAGCGGTTTACGACCGTCGATTCGTTGATGGCA
GACATGAATGCGGACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A059Y0K5

Antitoxin

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Source
ID
Structure
No matching records found

References