Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 835328..835991 Replicon chromosome
Accession NZ_CP007215
Organism Kosakonia sacchari SP1

Toxin (Protein)


Gene name cptA Uniprot ID A0A1G4Y1E1
Locus tag C813_RS26940 Protein ID WP_017457617.1
Coordinates 835575..835991 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1G4Y1L0
Locus tag C813_RS26935 Protein ID WP_017457616.1
Coordinates 835328..835594 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C813_RS26915 830859..832292 - 1434 WP_017457612.1 6-phospho-beta-glucosidase -
C813_RS26920 832409..833137 - 729 WP_025263844.1 MurR/RpiR family transcriptional regulator -
C813_RS26925 833377..834036 + 660 WP_017457614.1 hemolysin III family protein -
C813_RS26930 834098..835081 - 984 WP_017457615.1 tRNA-modifying protein YgfZ -
C813_RS26935 835328..835594 + 267 WP_017457616.1 FAD assembly factor SdhE Antitoxin
C813_RS26940 835575..835991 + 417 WP_017457617.1 protein YgfX Toxin
C813_RS26945 836005..836526 - 522 WP_017457618.1 flavodoxin FldB -
C813_RS26950 836626..837522 + 897 WP_017457619.1 site-specific tyrosine recombinase XerD -
C813_RS26955 837547..838260 + 714 WP_017457620.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
C813_RS26960 838266..839999 + 1734 WP_017457621.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16372.32 Da        Isoelectric Point: 11.0079

>T46168 WP_017457617.1 NZ_CP007215:835575-835991 [Kosakonia sacchari SP1]
VVLWQSDLRVSWRAQWISLLLHGLVAAFILFMPWPLSYTPLWLLLLSLVVFDCVRSQRRINACHGEIKLLMDSRLRWQGV
EWDIVGTPWMIRGGMMLRLRRAEDGRRQHLWLAADSMDSQEWRDLRRMIIQNPAQGLH

Download         Length: 417 bp

>T46168 NZ_CP007215:835575-835991 [Kosakonia sacchari SP1]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCACAATGGATTTCGTTATTACTGCACGGATTGGTGGCGGC
CTTCATTCTTTTTATGCCATGGCCGTTGAGCTATACGCCGCTGTGGCTTTTGCTGCTGTCGCTGGTGGTTTTCGACTGCG
TACGCAGCCAGCGGCGGATTAACGCCTGCCACGGCGAAATCAAACTGCTCATGGATTCCCGCCTGCGCTGGCAAGGTGTG
GAGTGGGATATTGTCGGTACACCCTGGATGATTCGCGGCGGCATGATGTTGCGTTTACGCCGTGCGGAAGATGGGCGGCG
CCAGCATTTATGGCTGGCGGCAGACAGCATGGATTCGCAGGAGTGGCGCGATCTACGCCGGATGATTATCCAAAATCCGG
CGCAGGGGCTGCATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10521.95 Da        Isoelectric Point: 6.0701

>AT46168 WP_017457616.1 NZ_CP007215:835328-835594 [Kosakonia sacchari SP1]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDHDKQVFVRLLESDDPDLFNWLMNHGKPQDAELQRMVQLIQTRN
RDRGPVAI

Download         Length: 267 bp

>AT46168 NZ_CP007215:835328-835594 [Kosakonia sacchari SP1]
ATGGATATTAATAATAAAGCCCGCATCCATTGGGCCTGTCGCCGCGGAATGCGCGAACTCGATATCTCCATCATGCCTTT
TTTTGAACATGAGTACGACTCGCTCAGTGACCACGACAAACAGGTGTTTGTGCGTCTGCTGGAGAGTGATGATCCGGATT
TATTCAACTGGTTGATGAATCATGGCAAACCCCAGGACGCGGAGTTGCAGCGAATGGTGCAGTTAATTCAGACACGGAAT
CGGGATCGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1G4Y1E1

Antitoxin

Source ID Structure
AlphaFold DB A0A1G4Y1L0

References