Detailed information of TA system TA046167

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 58174..58946
• Replicon: plasmid bpln_1p
• Accession: NZ_CP007214
• Organism: Burkholderia plantarii strain ATCC 43733

Toxin (Protein)

• Gene name: TacT2
• Uniprot ID: -
• Locus tag: bpln_RS32830
• Protein ID: WP_055141348.1
• Coordinates: 58452..58946 (+)
• Length: 165 a.a.

Antitoxin (Protein)

• Gene name: TacA2
• Uniprot ID: -
• Locus tag: bpln_RS32825
• Protein ID: WP_055141347.1
• Coordinates: 58174..58455 (+)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
bpln_RS32820	57633..57995	+	363	WP_148654283.1	hypothetical protein	-
bpln_RS32825	58174..58455	+	282	WP_055141347.1	DUF1778 domain-containing protein	Antitoxin
bpln_RS32830	58452..58946	+	495	WP_055141348.1	GNAT family N-acetyltransferase	Toxin
bpln_RS34820	59039..59509	+	471	WP_082465580.1	ProQ activator of osmoprotectant transporter prop	-
bpln_RS32835	59782..62703	-	2922	WP_055141349.1	conjugative relaxase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..197362	197362

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (44-144)

Antitoxin

• Vibrio phage ICP1, Orf50 (10-84)

Sequences

Toxin

Protein

• Length: 165 a.a.
• Molecular weight: 17488.02 Da
• Isoelectric Point: 9.6894

>T46167 WP_055141348.1 NZ_CP007214:58452-58946 [Burkholderia plantarii]
MTGWRAPEPLSDAHGLDDFDSGVASLDTWLKRRALANQRSGASRTFVATRDGRVGAYYALASGAVTPEVAPGRFRRNMPD
PIPVVVLGRLAVDRAHQGNGVGRALVRDAGLRVLHAAAAIGIRGLIVHALTDSAKAFYERVGFEASPIDPMLLLITLADL
EHAL

Nucleotide

• Length: 495 bp

>T46167 NZ_CP007214:58452-58946 [Burkholderia plantarii]
ATGACGGGCTGGCGCGCGCCCGAACCGCTCAGCGACGCGCATGGACTCGACGATTTCGATTCCGGCGTCGCGAGCCTCGA
CACGTGGCTCAAACGTCGTGCATTGGCCAATCAACGAAGCGGTGCGTCGCGGACCTTTGTGGCGACGAGAGACGGGCGGG
TGGGGGCGTACTACGCACTCGCGTCCGGCGCGGTTACGCCCGAGGTCGCACCGGGCCGCTTCCGGCGCAACATGCCCGAT
CCGATACCCGTGGTTGTGCTCGGGCGTCTCGCCGTCGATCGCGCTCATCAGGGCAATGGGGTTGGGCGTGCGCTGGTACG
CGATGCCGGTTTGCGTGTGCTGCACGCCGCAGCGGCCATCGGGATTCGCGGCCTGATTGTCCATGCGCTCACGGATTCGG
CCAAGGCGTTCTACGAGCGGGTCGGCTTTGAGGCGTCGCCGATCGATCCGATGCTGCTCCTGATCACGCTGGCCGACCTC
GAGCACGCCTTGTGA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10140.45 Da
• Isoelectric Point: 7.0104

>AT46167 WP_055141347.1 NZ_CP007214:58174-58455 [Burkholderia plantarii]
MTSTTPRDTLNLRIRPDDRSLIDRAAVAAHKTRTDFVLDAARAAAEQTLLDQVVLSAEPQAYAAFLARLDAPAQPNAALR
QTMQTRAPWDPAA

Nucleotide

• Length: 282 bp

>AT46167 NZ_CP007214:58174-58455 [Burkholderia plantarii]
ATGACCTCGACCACCCCACGCGACACCCTGAACCTACGCATTCGTCCCGACGATCGCAGCTTGATCGACCGCGCCGCAGT
AGCCGCCCACAAAACGCGTACGGATTTCGTCTTGGACGCAGCACGGGCCGCCGCCGAACAGACCTTGCTCGACCAGGTTG
TTTTGAGTGCCGAGCCGCAGGCCTACGCGGCCTTCCTGGCGCGCCTCGATGCGCCCGCCCAACCGAACGCGGCATTGCGG
CAGACCATGCAGACGCGCGCGCCCTGGGACCCCGCCGCATGA