Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 156224..158001 Replicon chromosome
Accession NZ_CP007213
Organism Burkholderia plantarii strain ATCC 43733

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag bpln_RS18440 Protein ID WP_055139627.1
Coordinates 156224..157144 (+) Length 307 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag bpln_RS18445 Protein ID WP_055139628.1
Coordinates 157141..158001 (+) Length 287 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
bpln_RS18415 151259..152218 + 960 WP_055139624.1 PDR/VanB family oxidoreductase -
bpln_RS18420 152364..153338 + 975 WP_055139625.1 IclR family transcriptional regulator -
bpln_RS18425 153398..154471 - 1074 WP_055139626.1 porin -
bpln_RS18430 154867..155637 + 771 WP_042626898.1 SDR family oxidoreductase -
bpln_RS18435 155674..156213 + 540 WP_042629202.1 cupin domain-containing protein -
bpln_RS18440 156224..157144 + 921 WP_055139627.1 alpha/beta hydrolase Toxin
bpln_RS18445 157141..158001 + 861 WP_055139628.1 IclR family transcriptional regulator Antitoxin
bpln_RS18450 158002..158817 + 816 WP_055139629.1 SDR family oxidoreductase -
bpln_RS18455 158810..160468 + 1659 WP_055139630.1 thiamine pyrophosphate-binding protein -
bpln_RS18460 160461..161288 + 828 WP_055139631.1 aspartate dehydrogenase -
bpln_RS18465 161304..162800 + 1497 WP_042626904.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(57-286)

Antitoxin

Transcription regulator IclR, C-terminal

(145-267)


Sequences

Toxin        


Download         Length: 307 a.a.        Molecular weight: 31218.47 Da        Isoelectric Point: 7.2359

>T46165 WP_055139627.1 NZ_CP007213:156224-157144 [Burkholderia plantarii]
MHDHPSHAGPTDGAPDLGARLPAFPARRIDVAPARAVGYREAGAPPAAGPHAGRLPIVLLHGIGSGAASWVQQLDTLGAA
RRVLAWDTPGYGESSPVAPASPQAGDYAAVLADWLDALGVARCVLVGHSLGAIVAGRFAATHGARVAGLLLLSPAAGYGA
ASEAVRAQKRDARLAMLAELGPQGLAERRSANMLSPSASEPARQWVRWNMARVVPAGYAQATHLLANADLAADLAGRRGP
VMVAVGEHDGITPPEACARLARAAGVPLQLIPNAGHAGYIEAPAACDALIDAFARRCETPDPEASA

Download         Length: 921 bp

>T46165 NZ_CP007213:156224-157144 [Burkholderia plantarii]
ATGCACGACCACCCCAGCCACGCCGGCCCGACCGACGGCGCGCCGGACCTCGGCGCCCGGCTCCCGGCGTTCCCCGCGCG
GCGGATCGACGTGGCGCCGGCGCGCGCCGTCGGCTATCGAGAAGCCGGCGCGCCGCCTGCCGCCGGCCCGCATGCCGGCC
GCCTGCCGATCGTGCTGCTGCACGGCATCGGCTCCGGCGCGGCGTCGTGGGTGCAGCAGCTCGACACGCTCGGCGCCGCG
CGCCGCGTGCTCGCCTGGGATACGCCGGGCTACGGCGAATCGAGCCCGGTCGCGCCGGCCTCCCCGCAGGCCGGCGACTA
CGCCGCCGTGCTGGCGGACTGGCTCGACGCGCTCGGCGTCGCGCGCTGCGTGCTGGTCGGGCATTCGCTCGGCGCGATCG
TCGCCGGCCGCTTCGCCGCCACGCATGGCGCGCGCGTCGCCGGCCTGCTGCTGCTGTCGCCCGCGGCCGGCTACGGCGCC
GCGAGCGAGGCGGTGCGCGCGCAGAAGCGCGACGCGCGCCTCGCGATGCTGGCCGAACTCGGCCCGCAGGGGCTCGCCGA
GCGGCGCAGCGCCAACATGCTGTCGCCGTCCGCGAGCGAGCCGGCCCGGCAATGGGTGCGCTGGAACATGGCGCGCGTCG
TGCCGGCCGGCTACGCGCAGGCCACGCACCTGCTGGCCAACGCGGATCTGGCCGCCGATCTGGCGGGCCGTCGCGGGCCG
GTGATGGTGGCGGTCGGCGAGCACGACGGCATCACGCCGCCCGAAGCCTGCGCGCGCCTCGCGCGGGCGGCGGGCGTGCC
GCTGCAACTGATCCCGAACGCCGGCCACGCCGGCTACATCGAGGCGCCGGCGGCCTGCGACGCGCTGATCGACGCGTTCG
CGCGGCGTTGCGAGACGCCGGACCCGGAGGCGAGCGCATGA

Antitoxin


Download         Length: 287 a.a.        Molecular weight: 31024.41 Da        Isoelectric Point: 6.5931

>AT46165 WP_055139628.1 NZ_CP007213:157141-158001 [Burkholderia plantarii]
MTPASTDRAAPDAPAPGEVSYLVPGLDRGLRILTEFSAREPILGAPELSRRLGIPRTTVFRLLQTLESLGFIERANGERN
YRLGVAVLRLGFEFLSSLELTDLGLPLIEALRDSTGLSTHIVIRDGRDVVFVAKAQSHASAFSAVKVNVGTRLPAHATTH
GHVLMGDLTLDELRALYAGVTLERFTRHTPGTVDELFERVRADAEQGHAISESSFEHGISVVSAPVFGDAGRIVAVVTAT
VPRAHFDTTLPAADLIDKVRATAFQLSLRLNYRPPAETRFMNALEI

Download         Length: 861 bp

>AT46165 NZ_CP007213:157141-158001 [Burkholderia plantarii]
ATGACGCCGGCATCGACCGACCGCGCCGCGCCGGATGCCCCGGCGCCGGGCGAAGTCAGCTATCTGGTGCCCGGGCTCGA
TCGCGGGCTGCGCATCCTCACCGAATTCTCGGCACGCGAGCCGATCCTGGGCGCGCCGGAGCTGTCGCGCCGGCTCGGCA
TTCCGCGCACCACGGTGTTCCGGCTGCTGCAGACGCTCGAATCGCTCGGCTTCATCGAGCGCGCCAACGGCGAGCGCAAT
TACCGGCTCGGCGTGGCGGTGTTGCGGCTCGGCTTCGAATTCCTCAGTTCGCTGGAGCTGACCGACCTGGGCCTGCCGCT
GATCGAGGCGCTGCGCGACAGCACCGGCCTGTCCACCCACATCGTGATCCGCGACGGCCGCGACGTGGTGTTCGTCGCCA
AGGCGCAGAGCCACGCGAGCGCGTTCAGCGCGGTGAAGGTCAACGTCGGCACGCGGCTGCCCGCCCACGCCACCACCCAC
GGCCACGTGCTGATGGGCGACCTGACGCTCGACGAACTGCGCGCGCTGTACGCGGGCGTCACGCTGGAACGCTTCACGCG
GCATACGCCCGGCACCGTCGACGAGCTGTTCGAGCGCGTGCGCGCCGACGCCGAGCAGGGCCACGCGATCAGCGAATCGT
CGTTCGAACACGGCATTTCGGTGGTCAGCGCGCCGGTGTTCGGCGACGCGGGGCGGATCGTGGCGGTGGTCACGGCCACG
GTGCCGCGCGCGCATTTCGACACCACGCTGCCCGCCGCCGACCTGATCGACAAGGTGCGGGCGACCGCGTTTCAACTCTC
GCTGCGGCTCAACTACCGGCCGCCGGCGGAAACCCGCTTCATGAATGCTTTGGAAATCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References