Detailed information of TA system TA046156

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 1136385..1136917
• Replicon: chromosome
• Accession: NZ_CP007201
• Organism: Sulfurospirillum multivorans DSM 12446

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: SMUL_RS05750
• Protein ID: WP_190278605.1
• Coordinates: 1136385..1136639 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: SMUL_RS05755
• Protein ID: WP_190278606.1
• Coordinates: 1136636..1136917 (+)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SMUL_RS05730	1134251..1134607	+	357	WP_025344304.1	hypothetical protein	-
SMUL_RS05735	1134620..1135234	-	615	WP_025344305.1	hypothetical protein	-
SMUL_RS05740	1135394..1135843	+	450	WP_025344306.1	hypothetical protein	-
SMUL_RS05745	1135879..1136241	+	363	WP_025344307.1	hypothetical protein	-
SMUL_RS05750	1136385..1136639	+	255	WP_190278605.1	BrnT family toxin	Toxin
SMUL_RS05755	1136636..1136917	+	282	WP_190278606.1	CopG family transcriptional regulator	Antitoxin
SMUL_RS05760	1136927..1137433	-	507	WP_025344310.1	hypothetical protein	-
SMUL_RS05765	1137450..1137764	-	315	WP_025344311.1	hypothetical protein	-
SMUL_RS05770	1137774..1137956	-	183	WP_148295270.1	hypothetical protein	-
SMUL_RS16960	1138565..1138816	+	252	WP_084613085.1	hypothetical protein	-
SMUL_RS05780	1138974..1139168	+	195	WP_025344313.1	hypothetical protein	-
SMUL_RS05785	1139134..1139613	+	480	WP_025344314.1	hypothetical protein	-
SMUL_RS05790	1139657..1140274	-	618	WP_025344315.1	hypothetical protein	-
SMUL_RS05795	1140411..1141094	-	684	WP_025344316.1	phospholipase D family protein	-
SMUL_RS16540	1141122..1141886	-	765	WP_025344317.1	restriction endonuclease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (4-80)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10082.53 Da
• Isoelectric Point: 6.8616

>T46156 WP_190278605.1 NZ_CP007201:1136385-1136639 [Sulfurospirillum multivorans DSM 12446]
MFEYDETKSKANKEKHGIDFEEAQALWQNKQHAVFDSVYVNNEWRHLLVGLIGELCYVAIFTMREDHIRIISVRRCRKNE
KEIL

Nucleotide

• Length: 255 bp

>T46156 NZ_CP007201:1136385-1136639 [Sulfurospirillum multivorans DSM 12446]
ATGTTTGAATACGATGAAACAAAGAGTAAAGCCAACAAAGAAAAACATGGAATAGACTTTGAAGAAGCACAAGCTCTTTG
GCAAAATAAACAACATGCCGTTTTTGATAGTGTTTATGTGAATAATGAATGGCGACATCTTTTAGTTGGTCTTATTGGTG
AGCTTTGTTATGTAGCTATTTTTACCATGCGTGAAGACCATATCCGTATTATCAGCGTTAGACGATGTCGAAAAAATGAA
AAGGAGATATTATGA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10771.55 Da
• Isoelectric Point: 9.6241

>AT46156 WP_190278606.1 NZ_CP007201:1136636-1136917 [Sulfurospirillum multivorans DSM 12446]
MKTISAEEFDRKFDNGEDILPYIDLSSKRTLKEFEKEMLAVKKVNVDLPSWAIASLDQEAKRMGVTRQSIIKMWLIQKLD
DLSLNRKSLKQVG

Nucleotide

• Length: 282 bp

>AT46156 NZ_CP007201:1136636-1136917 [Sulfurospirillum multivorans DSM 12446]
ATGAAAACAATATCAGCAGAAGAATTTGATAGAAAATTTGATAATGGTGAAGACATCTTACCTTACATTGATCTCTCTTC
AAAAAGAACGCTTAAAGAGTTTGAGAAAGAGATGTTAGCTGTAAAAAAAGTAAATGTGGATCTTCCATCTTGGGCTATTG
CCTCTTTAGATCAAGAAGCAAAACGTATGGGTGTTACGCGTCAATCTATCATTAAAATGTGGCTTATTCAGAAGCTTGAT
GATCTTAGTCTTAACCGTAAGTCTTTAAAACAAGTGGGATAA