Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4721622..4721972 Replicon chromosome
Accession NZ_CP007166
Organism Xanthomonas oryzae pv. oryzae PXO86

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag AZ54_RS21575 Protein ID WP_011257368.1
Coordinates 4721622..4721756 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag AZ54_RS21580 Protein ID WP_011407410.1
Coordinates 4721820..4721972 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AZ54_RS21560 4718636..4719658 - 1023 WP_075240574.1 MBL fold metallo-hydrolase -
AZ54_RS21565 4719711..4721000 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
AZ54_RS21570 4721169..4721378 - 210 WP_011407411.1 CsbD family protein -
AZ54_RS21575 4721622..4721756 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
AZ54_RS21580 4721820..4721972 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
AZ54_RS21585 4722080..4723003 - 924 WP_011407409.1 arginase -
AZ54_RS21590 4723325..4723999 + 675 WP_011257366.1 hypothetical protein -
AZ54_RS21595 4723996..4724235 + 240 WP_011257365.1 hypothetical protein -
AZ54_RS21600 4724242..4724538 + 297 WP_012446308.1 hypothetical protein -
AZ54_RS21605 4725018..4725701 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T46130 WP_011257368.1 NZ_CP007166:c4721756-4721622 [Xanthomonas oryzae pv. oryzae PXO86]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T46130 NZ_CP007166:c4721756-4721622 [Xanthomonas oryzae pv. oryzae PXO86]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT46130 WP_011407410.1 NZ_CP007166:c4721972-4721820 [Xanthomonas oryzae pv. oryzae PXO86]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT46130 NZ_CP007166:c4721972-4721820 [Xanthomonas oryzae pv. oryzae PXO86]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References