Detailed information of TA system TA046129

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2127574..2128130
• Replicon: chromosome
• Accession: NZ_CP007166
• Organism: Xanthomonas oryzae pv. oryzae PXO86

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: AZ54_RS09750
• Protein ID: WP_027703932.1
• Coordinates: 2127840..2128130 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: AZ54_RS09745
• Protein ID: WP_011408759.1
• Coordinates: 2127574..2127852 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AZ54_RS09730	2122726..2123910	+	1185	WP_011408397.1	IS256 family transposase	-
AZ54_RS09735	2124314..2125282	+	969	WP_012445118.1	IS5-like element ISXo1 family transposase	-
AZ54_RS09740	2125684..2126640	+	957	WP_041182719.1	IS30-like element IS1112b family transposase	-
AZ54_RS25030	2126889..2127089	+	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
AZ54_RS28680	2127034..2127378	+	345	WP_198912817.1	hypothetical protein	-
AZ54_RS28685	2127290..2127493	+	204	WP_198912807.1	hypothetical protein	-
AZ54_RS09745	2127574..2127852	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
AZ54_RS09750	2127840..2128130	+	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AZ54_RS28340	2128391..2128588	+	198	WP_153296741.1	hypothetical protein	-
AZ54_RS09760	2128732..2128911	+	180	WP_015463309.1	hypothetical protein	-
AZ54_RS09770	2129775..2130176	-	402	WP_011259345.1	H-NS histone family protein	-
AZ54_RS28515	2130398..2130574	+	177	Protein_1908	DUF3606 domain-containing protein	-
AZ54_RS28245	2130590..2130796	+	207	Protein_1909	hypothetical protein	-
AZ54_RS09780	2130856..2131172	+	317	Protein_1910	ATP-dependent DNA ligase	-
AZ54_RS09785	2131269..2132360	-	1092	WP_011408756.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T46129 WP_027703932.1 NZ_CP007166:2127840-2128130 [Xanthomonas oryzae pv. oryzae PXO86]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T46129 NZ_CP007166:2127840-2128130 [Xanthomonas oryzae pv. oryzae PXO86]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT46129 WP_011408759.1 NZ_CP007166:2127574-2127852 [Xanthomonas oryzae pv. oryzae PXO86]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT46129 NZ_CP007166:2127574-2127852 [Xanthomonas oryzae pv. oryzae PXO86]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2