Detailed information of TA system TA046107

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): hicAB/HicA-HicA
• Location: 2232546..2232992
• Replicon: chromosome
• Accession: NZ_CP007139
• Organism: Fimbriimonas ginsengisoli Gsoil 348

Toxin (Protein)

• Gene name: hicA
• Uniprot ID: -
• Locus tag: OP10G_RS25775
• Protein ID: WP_084179051.1
• Coordinates: 2232807..2232992 (-)
• Length: 62 a.a.

Antitoxin (Protein)

• Gene name: hicB
• Uniprot ID: -
• Locus tag: OP10G_RS25770
• Protein ID: WP_084179048.1
• Coordinates: 2232546..2232764 (-)
• Length: 73 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OP10G_RS10220	2228296..2228979	-	684	WP_144241088.1	hypothetical protein	-
OP10G_RS10225	2228982..2229812	-	831	WP_025225988.1	carbohydrate-binding family 9-like protein	-
OP10G_RS10230	2229882..2230415	+	534	WP_025225987.1	hypothetical protein	-
OP10G_RS10235	2230412..2230981	-	570	WP_025225986.1	acyloxyacyl hydrolase	-
OP10G_RS10240	2231053..2232405	+	1353	WP_038474925.1	ribosome biogenesis GTPase Der	-
OP10G_RS25770	2232546..2232764	-	219	WP_084179048.1	type II toxin-antitoxin system HicB family antitoxin	Antitoxin
OP10G_RS25775	2232807..2232992	-	186	WP_084179051.1	type II toxin-antitoxin system HicA family toxin	Toxin
OP10G_RS10245	2233008..2233790	-	783	WP_025225984.1	ABC transporter permease	-
OP10G_RS10250	2233815..2235029	-	1215	WP_025225983.1	M48 family metalloprotease	-
OP10G_RS24390	2235092..2236771	-	1680	WP_025225982.1	alcohol dehydrogenase catalytic domain-containing protein	-
OP10G_RS10260	2236768..2237829	-	1062	WP_052547677.1	alcohol dehydrogenase catalytic domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HicA mRNA interferase family (4-60)

Antitoxin

• HicB-like antitoxin of toxin-antitoxin system (4-67)

Sequences

Toxin

Protein

• Length: 62 a.a.
• Molecular weight: 6848.94 Da
• Isoelectric Point: 10.9062

>T46107 WP_084179051.1 NZ_CP007139:c2232992-2232807 [Fimbriimonas ginsengisoli Gsoil 348]
MQVRDLLDKLRKEGWVLDHQSGSHRQFVHPTKPGIVTVPGPPNKEIPPGTLNSIKKQAGWK

Nucleotide

• Length: 186 bp

>T46107 NZ_CP007139:c2232992-2232807 [Fimbriimonas ginsengisoli Gsoil 348]
ATGCAAGTTCGAGACCTGCTCGATAAACTTAGAAAGGAGGGGTGGGTGCTTGACCACCAATCGGGAAGCCATCGGCAGTT
CGTTCATCCAACGAAACCGGGCATTGTGACGGTTCCGGGACCTCCCAACAAAGAGATACCACCGGGAACGTTGAATAGCA
TCAAAAAACAGGCTGGCTGGAAATAG

Antitoxin

Protein

• Length: 73 a.a.
• Molecular weight: 7633.74 Da
• Isoelectric Point: 4.5289

>AT46107 WP_084179048.1 NZ_CP007139:c2232764-2232546 [Fimbriimonas ginsengisoli Gsoil 348]
MHQYVVIYERPEGALNWGAYVPDLPGCIAVGDSLDEVKAEMATAIALHLEALQRHGYAIPLPSSVAGTVSVA

Nucleotide

• Length: 219 bp

>AT46107 NZ_CP007139:c2232764-2232546 [Fimbriimonas ginsengisoli Gsoil 348]
ATGCATCAATACGTCGTCATTTACGAAAGGCCGGAGGGTGCGCTAAATTGGGGAGCCTACGTCCCGGATCTTCCCGGTTG
TATTGCGGTGGGCGACTCCCTCGATGAAGTCAAAGCGGAAATGGCAACAGCTATCGCACTTCATCTAGAAGCCCTCCAAC
GCCACGGGTACGCCATACCCCTCCCATCTAGCGTCGCAGGCACCGTTTCCGTTGCGTGA