Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 2038459..2039126 Replicon chromosome
Accession NZ_CP007139
Organism Fimbriimonas ginsengisoli Gsoil 348

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag OP10G_RS09345 Protein ID WP_173425323.1
Coordinates 2038785..2039126 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag OP10G_RS09340 Protein ID WP_025226154.1
Coordinates 2038459..2038788 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OP10G_RS09320 2033740..2035356 + 1617 WP_025226156.1 FAD-dependent oxidoreductase -
OP10G_RS09325 2035368..2036099 + 732 WP_025226155.1 hypothetical protein -
OP10G_RS09330 2036343..2037878 - 1536 WP_052547653.1 phosphoenolpyruvate carboxykinase (ATP) -
OP10G_RS09335 2038148..2038375 - 228 WP_038472885.1 phosphoribosylformylglycinamidine synthase subunit PurS -
OP10G_RS09340 2038459..2038788 - 330 WP_025226154.1 helix-turn-helix domain-containing protein Antitoxin
OP10G_RS09345 2038785..2039126 - 342 WP_173425323.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OP10G_RS09350 2039167..2040048 - 882 WP_025226153.1 DMT family transporter -
OP10G_RS09355 2040145..2040882 + 738 WP_025226152.1 hypothetical protein -
OP10G_RS09360 2040883..2041431 + 549 WP_038472890.1 guanylate kinase -
OP10G_RS09365 2041483..2042178 + 696 WP_052547655.1 transposase -
OP10G_RS09370 2042175..2043350 + 1176 WP_025226151.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(6-99)

Antitoxin

Cro/C1-type helix-turn-helix domain

(32-88)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12688.50 Da        Isoelectric Point: 10.0506

>T46106 WP_173425323.1 NZ_CP007139:c2039126-2038785 [Fimbriimonas ginsengisoli Gsoil 348]
IASSRKDLKSFPEGVQGDVGFALYRAQEGKKHVAAKPLKGFGDAGVLEVVATDDGDAYRAVYTVRFAEAVFVLHCFQKKS
KSGIATPKQEVELIRSRLKQAEEEYKRWQEKRK

Download         Length: 342 bp

>T46106 NZ_CP007139:c2039126-2038785 [Fimbriimonas ginsengisoli Gsoil 348]
ATCGCCTCCAGCAGGAAAGACTTGAAATCCTTTCCCGAAGGGGTTCAGGGCGATGTGGGTTTTGCGCTGTATCGAGCCCA
GGAGGGCAAGAAACACGTAGCGGCAAAACCGCTAAAAGGATTCGGCGATGCTGGAGTCCTCGAAGTTGTCGCCACTGATG
ACGGCGATGCTTATCGGGCAGTTTATACGGTGCGGTTCGCGGAGGCTGTCTTCGTTTTGCATTGCTTTCAGAAGAAATCC
AAGTCCGGCATCGCAACCCCGAAGCAGGAAGTCGAACTGATTAGAAGCCGGCTTAAGCAAGCCGAAGAGGAGTACAAGCG
GTGGCAAGAGAAGAGGAAATGA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12015.87 Da        Isoelectric Point: 6.4666

>AT46106 WP_025226154.1 NZ_CP007139:c2038788-2038459 [Fimbriimonas ginsengisoli Gsoil 348]
MIEEIVERGSGNVFADLGLSNPEERLAKAKIASAIQDVIEARGLTQNQAADLMGVDQPKVSKIIRGRLSEFSTERLLHFL
ICFGLDVEIVIHKRAKPDQRQGAITVAYV

Download         Length: 330 bp

>AT46106 NZ_CP007139:c2038788-2038459 [Fimbriimonas ginsengisoli Gsoil 348]
ATGATTGAAGAAATCGTGGAGCGTGGAAGTGGAAACGTGTTTGCCGACTTGGGTCTGTCCAATCCCGAAGAGCGTCTTGC
GAAGGCAAAGATCGCCAGTGCTATCCAAGATGTTATTGAAGCGCGTGGTCTTACCCAGAACCAAGCGGCGGATCTAATGG
GGGTTGACCAGCCCAAGGTATCCAAGATCATCAGGGGTCGTTTGAGTGAATTCTCCACCGAGCGTTTGCTCCACTTCCTC
ATATGTTTCGGATTGGACGTGGAGATCGTCATTCACAAGAGGGCCAAGCCCGATCAACGGCAAGGCGCGATCACCGTGGC
CTACGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References