Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YefM-YoeB
Location 1990045..1990556 Replicon chromosome
Accession NZ_CP007139
Organism Fimbriimonas ginsengisoli Gsoil 348

Toxin (Protein)


Gene name relE Uniprot ID A0A068NR32
Locus tag OP10G_RS09090 Protein ID WP_025226202.1
Coordinates 1990045..1990305 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A068NP44
Locus tag OP10G_RS09095 Protein ID WP_025226201.1
Coordinates 1990302..1990556 (+) Length 85 a.a.

Genomic Context

OP10G_RS09065OP10G_RS09080OP10G_RS09085OP10G_RS09090OP10G_RS09095OP10G_RS09100OP10G_RS09105OP10G_RS26750OP10G_RS26220OP10G_RS09070OP10G_RS09075OP10G_RS09115
Location: 1985133..1985573 (441 bp)
Type: Others
Protein ID: WP_025226207.1
Location: 1988528..1989061 (534 bp)
Type: Others
Protein ID: WP_025226204.1
Location: 1989054..1989998 (945 bp)
Type: Others
Protein ID: WP_025226203.1
Location: 1990045..1990305 (261 bp)
Type: Toxin
Protein ID: WP_025226202.1
Location: 1990302..1990556 (255 bp)
Type: Antitoxin
Protein ID: WP_025226201.1
Location: 1990606..1991925 (1320 bp)
Type: Others
Protein ID: WP_025226200.1
Location: 1991931..1992707 (777 bp)
Type: Others
Protein ID: WP_025226199.1
Location: 1992846..1993121 (276 bp)
Type: Others
Protein ID: WP_025226198.1
Location: 1993905..1994987 (1083 bp)
Type: Others
Protein ID: WP_144241072.1
Location: 1985576..1987522 (1947 bp)
Type: Others
Protein ID: WP_025226206.1
Location: 1987558..1988442 (885 bp)
Type: Others
Protein ID: WP_025226205.1
Location: 1993198..1993785 (588 bp)
Type: Others
Protein ID: WP_025226197.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OP10G_RS090651985133..1985573+441WP_025226207.1hypothetical protein-
OP10G_RS090701985576..1987522-1947WP_025226206.1amidohydrolase family protein-
OP10G_RS090751987558..1988442-885WP_025226205.1ferritin-like domain-containing protein-
OP10G_RS090801988528..1989061+534WP_025226204.1bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR-
OP10G_RS090851989054..1989998+945WP_025226203.1aspartate carbamoyltransferase catalytic subunit-
OP10G_RS090901990045..1990305+261WP_025226202.1type II toxin-antitoxin system prevent-host-death family antitoxinToxin
OP10G_RS090951990302..1990556+255WP_025226201.1Txe/YoeB family addiction module toxinAntitoxin
OP10G_RS091001990606..1991925+1320WP_025226200.1dihydroorotase-
OP10G_RS091051991931..1992707+777WP_025226199.1hypothetical protein-
OP10G_RS267501992846..1993121+276WP_025226198.1hypothetical protein-
OP10G_RS091151993198..1993785-588WP_025226197.1septum formation inhibitor Maf-
OP10G_RS262201993905..1994987+1083WP_144241072.1PD40 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)

Antitoxin

Toxin YoeB

(5-84)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9719.97 Da        Isoelectric Point: 4.3142

>T46104 WP_025226202.1 NZ_CP007139:1990045-1990305 [Fimbriimonas ginsengisoli Gsoil 348]
MDAISYSAARAKLARVMDQVCENREPMIITRQGSESVVILSLSDYEELDETAYLRRSPENARRLTEAIKQLEAGNGIEME
LKDLTD

Download         Length: 261 bp

>T46104 NZ_CP007139:1990045-1990305 [Fimbriimonas ginsengisoli Gsoil 348]
ATGGATGCGATCAGTTATTCAGCGGCGCGGGCAAAGCTGGCGCGGGTGATGGACCAAGTGTGCGAAAACCGCGAGCCGAT
GATCATCACTCGTCAAGGCAGCGAGTCGGTGGTGATTCTTTCCCTCTCCGATTACGAGGAGCTGGACGAAACCGCCTATC
TCCGCCGAAGCCCGGAAAATGCTCGGAGGCTTACGGAAGCGATTAAGCAGCTCGAGGCGGGGAACGGGATTGAGATGGAG
CTTAAGGATCTGACTGATTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9976.46 Da        Isoelectric Point: 9.4413

>AT46104 WP_025226201.1 NZ_CP007139:1990302-1990556 [Fimbriimonas ginsengisoli Gsoil 348]
MIISFSTRGWEDYLELQRVDAKATKRINKLIAEIVRDPFAGLGKPEPLRHEWVGYWSRRIDGEHRLVYKVTDTAIQIAQC
RYHY

Download         Length: 255 bp

>AT46104 NZ_CP007139:1990302-1990556 [Fimbriimonas ginsengisoli Gsoil 348]
TTGATCATCTCATTTTCCACCCGCGGCTGGGAGGACTATCTTGAATTGCAGCGGGTCGATGCCAAGGCAACCAAAAGAAT
TAACAAGCTGATTGCGGAAATCGTCCGCGATCCCTTTGCAGGCTTGGGCAAACCGGAACCCTTGCGGCATGAGTGGGTCG
GATATTGGTCGCGAAGGATCGACGGCGAGCACCGCCTCGTCTACAAGGTGACCGACACGGCGATTCAAATCGCGCAGTGC
CGGTACCACTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A068NR32

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A068NP44

References