Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YefM-YoeB
Location 1990045..1990556 Replicon chromosome
Accession NZ_CP007139
Organism Fimbriimonas ginsengisoli Gsoil 348

Toxin (Protein)


Gene name relE Uniprot ID A0A068NR32
Locus tag OP10G_RS09090 Protein ID WP_025226202.1
Coordinates 1990045..1990305 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A068NP44
Locus tag OP10G_RS09095 Protein ID WP_025226201.1
Coordinates 1990302..1990556 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OP10G_RS09065 1985133..1985573 + 441 WP_025226207.1 hypothetical protein -
OP10G_RS09070 1985576..1987522 - 1947 WP_025226206.1 amidohydrolase family protein -
OP10G_RS09075 1987558..1988442 - 885 WP_025226205.1 ferritin-like domain-containing protein -
OP10G_RS09080 1988528..1989061 + 534 WP_025226204.1 bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR -
OP10G_RS09085 1989054..1989998 + 945 WP_025226203.1 aspartate carbamoyltransferase catalytic subunit -
OP10G_RS09090 1990045..1990305 + 261 WP_025226202.1 type II toxin-antitoxin system prevent-host-death family antitoxin Toxin
OP10G_RS09095 1990302..1990556 + 255 WP_025226201.1 Txe/YoeB family addiction module toxin Antitoxin
OP10G_RS09100 1990606..1991925 + 1320 WP_025226200.1 dihydroorotase -
OP10G_RS09105 1991931..1992707 + 777 WP_025226199.1 hypothetical protein -
OP10G_RS26750 1992846..1993121 + 276 WP_025226198.1 hypothetical protein -
OP10G_RS09115 1993198..1993785 - 588 WP_025226197.1 septum formation inhibitor Maf -
OP10G_RS26220 1993905..1994987 + 1083 WP_144241072.1 PD40 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)

Antitoxin

Toxin YoeB

(5-84)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9719.97 Da        Isoelectric Point: 4.3142

>T46104 WP_025226202.1 NZ_CP007139:1990045-1990305 [Fimbriimonas ginsengisoli Gsoil 348]
MDAISYSAARAKLARVMDQVCENREPMIITRQGSESVVILSLSDYEELDETAYLRRSPENARRLTEAIKQLEAGNGIEME
LKDLTD

Download         Length: 261 bp

>T46104 NZ_CP007139:1990045-1990305 [Fimbriimonas ginsengisoli Gsoil 348]
ATGGATGCGATCAGTTATTCAGCGGCGCGGGCAAAGCTGGCGCGGGTGATGGACCAAGTGTGCGAAAACCGCGAGCCGAT
GATCATCACTCGTCAAGGCAGCGAGTCGGTGGTGATTCTTTCCCTCTCCGATTACGAGGAGCTGGACGAAACCGCCTATC
TCCGCCGAAGCCCGGAAAATGCTCGGAGGCTTACGGAAGCGATTAAGCAGCTCGAGGCGGGGAACGGGATTGAGATGGAG
CTTAAGGATCTGACTGATTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9976.46 Da        Isoelectric Point: 9.4413

>AT46104 WP_025226201.1 NZ_CP007139:1990302-1990556 [Fimbriimonas ginsengisoli Gsoil 348]
MIISFSTRGWEDYLELQRVDAKATKRINKLIAEIVRDPFAGLGKPEPLRHEWVGYWSRRIDGEHRLVYKVTDTAIQIAQC
RYHY

Download         Length: 255 bp

>AT46104 NZ_CP007139:1990302-1990556 [Fimbriimonas ginsengisoli Gsoil 348]
TTGATCATCTCATTTTCCACCCGCGGCTGGGAGGACTATCTTGAATTGCAGCGGGTCGATGCCAAGGCAACCAAAAGAAT
TAACAAGCTGATTGCGGAAATCGTCCGCGATCCCTTTGCAGGCTTGGGCAAACCGGAACCCTTGCGGCATGAGTGGGTCG
GATATTGGTCGCGAAGGATCGACGGCGAGCACCGCCTCGTCTACAAGGTGACCGACACGGCGATTCAAATCGCGCAGTGC
CGGTACCACTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A068NR32

Antitoxin

Source ID Structure
AlphaFold DB A0A068NP44

References