Detailed information of TA system TA046102

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN(toxin)
• Location: 1309509..1310176
• Replicon: chromosome
• Accession: NZ_CP007139
• Organism: Fimbriimonas ginsengisoli Gsoil 348

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: OP10G_RS05925
• Protein ID: WP_025226806.1
• Coordinates: 1309748..1310176 (+)
• Length: 143 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A068NMA1
• Locus tag: OP10G_RS05920
• Protein ID: WP_025226807.1
• Coordinates: 1309509..1309751 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OP10G_RS05900	1305009..1305359	+	351	WP_025226811.1	metalloregulator ArsR/SmtB family transcription factor	-
OP10G_RS05905	1305363..1305830	+	468	WP_025226810.1	GyrI-like domain-containing protein	-
OP10G_RS05910	1305827..1306321	+	495	WP_025226809.1	SRPBCC family protein	-
OP10G_RS24110	1306706..1309399	+	2694	WP_025226808.1	DUF5110 domain-containing protein	-
OP10G_RS05920	1309509..1309751	+	243	WP_025226807.1	hypothetical protein	Antitoxin
OP10G_RS05925	1309748..1310176	+	429	WP_025226806.1	hypothetical protein	Toxin
OP10G_RS05930	1310409..1311386	+	978	WP_158409150.1	DUF2330 domain-containing protein	-
OP10G_RS05935	1311440..1311919	-	480	WP_025226804.1	VOC family protein	-
OP10G_RS24115	1312356..1313540	+	1185	WP_025226803.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain toxin (2-138)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 143 a.a.
• Molecular weight: 15409.80 Da
• Isoelectric Point: 8.1801

>T46102 WP_025226806.1 NZ_CP007139:1309748-1310176 [Fimbriimonas ginsengisoli Gsoil 348]
VTALLDVNMLLALLDGSHVHHVRAKEWLLAQPKPTWASCPITQNGFIRIISQSAYPGSISTSQAFSLLGTAASSPHHRFW
PDDLSLLDGSLIDPTLVHGPKQVTDIYLLALAVKHNGRFVALDRAIPLSSVRGAQSHHLVLL

Nucleotide

• Length: 429 bp

>T46102 NZ_CP007139:1309748-1310176 [Fimbriimonas ginsengisoli Gsoil 348]
GTGACCGCTCTACTCGATGTGAACATGCTGCTCGCGTTGCTCGACGGGTCTCATGTCCATCACGTCCGCGCCAAGGAGTG
GCTGCTCGCGCAACCGAAGCCAACCTGGGCGTCGTGTCCCATTACGCAGAACGGGTTTATTCGGATTATCTCGCAGAGCG
CTTATCCGGGTTCGATCAGTACAAGCCAGGCCTTTTCCCTGCTTGGGACTGCCGCAAGTTCGCCTCACCATCGATTTTGG
CCCGACGATCTCAGTCTCCTTGACGGGTCCCTCATCGATCCAACTCTTGTTCATGGTCCCAAACAGGTTACGGACATTTA
CCTACTTGCCCTTGCCGTAAAACATAACGGACGGTTCGTGGCCTTGGACCGGGCAATTCCACTGAGCAGCGTTCGCGGCG
CCCAATCGCACCATTTGGTTCTTCTCTAA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8755.13 Da
• Isoelectric Point: 5.1316

>AT46102 WP_025226807.1 NZ_CP007139:1309509-1309751 [Fimbriimonas ginsengisoli Gsoil 348]
MRTTLDIAEDVLLAAKALGRLEHKTAGQVLSELARKGLAASKGGAEMSSEQEFLGFRPLPMRGVVVTSELIERLREDEFL

Nucleotide

• Length: 243 bp

>AT46102 NZ_CP007139:1309509-1309751 [Fimbriimonas ginsengisoli Gsoil 348]
ATGCGAACCACGTTGGACATTGCGGAGGACGTGCTGTTGGCAGCGAAAGCGCTGGGGAGATTGGAGCATAAGACTGCCGG
CCAGGTCCTGTCGGAGCTGGCCAGGAAGGGACTTGCCGCCTCGAAAGGAGGGGCTGAGATGAGCTCCGAGCAGGAATTCC
TCGGGTTTAGGCCATTGCCGATGCGTGGCGTGGTCGTCACGTCGGAACTGATCGAGCGGCTCCGTGAGGACGAGTTTCTG
TGA

Structures

Antitoxin

• AlphaFold DB: A0A068NMA1