Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2301346..2301614 Replicon chromosome
Accession NZ_CP007136
Organism Escherichia coli O145:H28 str. RM12581

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2301384..2301487 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2301346..2301614 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECRM12581_RS11730 2298503..2299942 + 1440 WP_024221588.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ECRM12581_RS11735 2300060..2300296 + 237 WP_001295499.1 DUF1480 family protein -
ECRM12581_RS11740 2300401..2300592 + 192 WP_001313035.1 YebW family protein -
ECRM12581_RS11745 2300593..2301249 - 657 WP_000812714.1 protein-serine/threonine phosphatase -
- 2301346..2301614 + 269 - - Antitoxin
- 2301384..2301487 - 104 - - Toxin
ECRM12581_RS11755 2301644..2301985 - 342 WP_000976475.1 YebY family protein -
ECRM12581_RS11760 2301998..2302870 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
ECRM12581_RS11765 2302874..2303248 - 375 WP_000168738.1 CopC domain-containing protein YobA -
ECRM12581_RS11770 2303387..2303617 + 231 WP_000916763.1 DNA polymerase III subunit theta -
ECRM12581_RS11775 2303719..2304375 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ECRM12581_RS11780 2304399..2305061 + 663 WP_000944252.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T46079 NZ_CP007136:c2301487-2301384 [Escherichia coli O145:H28 str. RM12581]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT46079 NZ_CP007136:2301346-2301614 [Escherichia coli O145:H28 str. RM12581]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References