Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2235386..2235654 | Replicon | chromosome |
| Accession | NZ_CP007133 | ||
| Organism | Escherichia coli O145:H28 str. RM12761 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2235424..2235527 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2235386..2235654 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ECRM12761_RS11340 | 2232543..2233982 | + | 1440 | WP_024221588.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| ECRM12761_RS11345 | 2234100..2234336 | + | 237 | WP_001295499.1 | DUF1480 family protein | - |
| ECRM12761_RS11350 | 2234441..2234632 | + | 192 | WP_001313035.1 | YebW family protein | - |
| ECRM12761_RS11355 | 2234633..2235289 | - | 657 | WP_000812714.1 | protein-serine/threonine phosphatase | - |
| - | 2235386..2235654 | + | 269 | - | - | Antitoxin |
| - | 2235424..2235527 | - | 104 | - | - | Toxin |
| ECRM12761_RS11365 | 2235684..2236025 | - | 342 | WP_000976475.1 | YebY family protein | - |
| ECRM12761_RS11370 | 2236038..2236910 | - | 873 | WP_000879330.1 | copper homeostasis membrane protein CopD | - |
| ECRM12761_RS11375 | 2236914..2237288 | - | 375 | WP_000168738.1 | CopC domain-containing protein YobA | - |
| ECRM12761_RS11380 | 2237427..2237657 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| ECRM12761_RS11385 | 2237759..2238415 | + | 657 | WP_000011656.1 | carbon-nitrogen hydrolase family protein | - |
| ECRM12761_RS11390 | 2238439..2239101 | + | 663 | WP_000944252.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleC / stx2B / stx2A | 2219547..2311141 | 91594 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T46043 NZ_CP007133:c2235527-2235424 [Escherichia coli O145:H28 str. RM12761]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 269 bp
>AT46043 NZ_CP007133:2235386-2235654 [Escherichia coli O145:H28 str. RM12761]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT
