Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1070097..1070899 Replicon plasmid unnamed
Accession NZ_CP007068
Organism Rhizobium leguminosarum bv. trifolii CB782

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag RLEG12_RS26010 Protein ID WP_025418376.1
Coordinates 1070372..1070899 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag RLEG12_RS26005 Protein ID WP_025418375.1
Coordinates 1070097..1070375 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RLEG12_RS25980 1065347..1065973 - 627 WP_025418372.1 TetR/AcrR family transcriptional regulator -
RLEG12_RS32220 1066040..1066446 + 407 Protein_979 hypothetical protein -
RLEG12_RS25990 1066483..1067748 + 1266 WP_025418373.1 FAD-dependent oxidoreductase -
RLEG12_RS25995 1067995..1068393 + 399 WP_003568527.1 VOC family protein -
RLEG12_RS26000 1068697..1069113 + 417 WP_025418374.1 ester cyclase -
RLEG12_RS33355 1069810..1070067 - 258 WP_128399627.1 methyl-accepting chemotaxis protein -
RLEG12_RS26005 1070097..1070375 + 279 WP_025418375.1 DUF1778 domain-containing protein Antitoxin
RLEG12_RS26010 1070372..1070899 + 528 WP_025418376.1 hypothetical protein Toxin
RLEG12_RS26015 1070904..1071128 + 225 Protein_986 cytochrome C -
RLEG12_RS26020 1071308..1071769 + 462 WP_080687626.1 autotransporter outer membrane beta-barrel domain-containing protein -
RLEG12_RS26025 1071982..1072575 - 594 WP_025418379.1 TetR/AcrR family transcriptional regulator -
RLEG12_RS26030 1072684..1073709 + 1026 WP_025418380.1 aldehyde reductase -
RLEG12_RS26035 1074452..1074958 - 507 WP_025418381.1 DUF1097 domain-containing protein -
RLEG12_RS26040 1075082..1075834 - 753 WP_025418382.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - gmd / htpB 1..1563772 1563772


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(11-85)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18658.57 Da        Isoelectric Point: 6.9493

>T46028 WP_025418376.1 NZ_CP007068:1070372-1070899 [Rhizobium leguminosarum bv. trifolii CB782]
VTLPAWHEEPIAKSHGRAAFDCGDVQMNEFLLRFARQSHEQNASKTFCAIDDAVPDRILGFYTIAPSAVEHAIVPDAMTR
GLARHDVPGFKLARLATDSAVAGQGLGGQLLATAALRCLRLAGEGGGLLLIIDAKGERAANWYACYGAEPLKDKPLTLVM
PLITLAADLRAKGLL

Download         Length: 528 bp

>T46028 NZ_CP007068:1070372-1070899 [Rhizobium leguminosarum bv. trifolii CB782]
GTGACTTTACCTGCATGGCATGAGGAACCGATCGCCAAGTCTCACGGTCGGGCGGCCTTCGATTGCGGCGACGTTCAGAT
GAATGAGTTCCTGCTCCGCTTTGCCCGACAAAGCCATGAGCAGAATGCCTCGAAGACCTTCTGTGCTATCGACGACGCAG
TGCCCGACCGCATTCTTGGGTTCTATACAATCGCGCCTTCGGCAGTCGAGCATGCAATCGTGCCTGATGCAATGACGCGC
GGTCTTGCCCGCCATGATGTGCCGGGCTTCAAGCTTGCGCGACTGGCCACCGACAGCGCGGTTGCGGGGCAGGGACTGGG
AGGCCAACTCCTGGCCACCGCAGCGCTCCGCTGCCTGCGACTTGCAGGAGAGGGCGGGGGACTTCTACTGATCATCGATG
CCAAAGGCGAGCGCGCCGCCAACTGGTACGCTTGCTATGGCGCCGAGCCGCTGAAGGACAAGCCGCTAACTCTCGTGATG
CCGCTCATCACATTGGCGGCCGACTTGCGTGCCAAAGGTCTCCTCTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10038.56 Da        Isoelectric Point: 8.6363

>AT46028 WP_025418375.1 NZ_CP007068:1070097-1070375 [Rhizobium leguminosarum bv. trifolii CB782]
MPSIANENSERMSLRVPATAKAKLVRAAALRNTDLTNFVTQSALREAEAVIEEAETIKVSNRDYLRILELLENPPKPNAK
LRAAIAGLPDGL

Download         Length: 279 bp

>AT46028 NZ_CP007068:1070097-1070375 [Rhizobium leguminosarum bv. trifolii CB782]
ATGCCCAGCATAGCGAACGAGAACAGTGAGCGTATGAGTTTGAGGGTGCCTGCCACGGCCAAGGCTAAACTCGTGCGCGC
TGCGGCACTTCGTAATACCGATCTGACGAATTTCGTAACCCAATCCGCCCTGCGAGAAGCAGAGGCTGTGATCGAAGAAG
CCGAGACGATCAAAGTGTCAAACCGCGATTATCTTCGCATTCTTGAGCTTCTGGAAAATCCGCCCAAACCCAACGCCAAG
CTGCGCGCGGCGATTGCCGGTTTGCCGGACGGCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References