Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-StbC |
| Location | 556306..556982 | Replicon | plasmid unnamed |
| Accession | NZ_CP007046 | ||
| Organism | Rhizobium leguminosarum bv. trifolii WSM1689 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | W0IS25 |
| Locus tag | RLEG3_RS26060 | Protein ID | WP_025397319.1 |
| Coordinates | 556557..556982 (+) | Length | 142 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | RLEG3_RS33970 | Protein ID | WP_025397318.1 |
| Coordinates | 556306..556560 (+) | Length | 85 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RLEG3_RS26025 | 551308..552150 | - | 843 | WP_025397313.1 | crotonase/enoyl-CoA hydratase family protein | - |
| RLEG3_RS26030 | 552238..552828 | + | 591 | WP_174446891.1 | TetR/AcrR family transcriptional regulator | - |
| RLEG3_RS26035 | 553086..553925 | + | 840 | WP_025397315.1 | transporter substrate-binding domain-containing protein | - |
| RLEG3_RS26040 | 554043..554705 | + | 663 | WP_025397316.1 | amino acid ABC transporter permease | - |
| RLEG3_RS26045 | 554711..555370 | + | 660 | WP_011648868.1 | amino acid ABC transporter permease | - |
| RLEG3_RS26050 | 555383..556153 | + | 771 | WP_025397317.1 | amino acid ABC transporter ATP-binding protein | - |
| RLEG3_RS33970 | 556306..556560 | + | 255 | WP_025397318.1 | hypothetical protein | Antitoxin |
| RLEG3_RS26060 | 556557..556982 | + | 426 | WP_025397319.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| RLEG3_RS26065 | 557178..557936 | + | 759 | WP_025397320.1 | GntR family transcriptional regulator | - |
| RLEG3_RS26070 | 557930..558715 | + | 786 | WP_025397321.1 | transporter substrate-binding domain-containing protein | - |
| RLEG3_RS26075 | 558794..559465 | + | 672 | WP_025397322.1 | amino acid ABC transporter permease | - |
| RLEG3_RS26080 | 559462..560121 | + | 660 | WP_025397323.1 | amino acid ABC transporter permease | - |
| RLEG3_RS26085 | 560099..560824 | + | 726 | WP_025397324.1 | amino acid ABC transporter ATP-binding protein | - |
| RLEG3_RS33975 | 561107..561463 | - | 357 | Protein_511 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| RLEG3_RS26090 | 561463..561720 | - | 258 | WP_025397325.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..667306 | 667306 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 142 a.a. Molecular weight: 14959.10 Da Isoelectric Point: 4.4617
>T46018 WP_025397319.1 NZ_CP007046:556557-556982 [Rhizobium leguminosarum bv. trifolii WSM1689]
MIIVDTNVVSEAMKPAPDEAVKFWLDEQAAETLFLSSVTIAELMFGIGALPAGKRKERLSDALDGLMELFESRILAFDIT
AARRYADFAVKARAAGRGFPTPDGYIAAIAASKGFAVATRDTSAFDAAGVEVINPWAASTA
MIIVDTNVVSEAMKPAPDEAVKFWLDEQAAETLFLSSVTIAELMFGIGALPAGKRKERLSDALDGLMELFESRILAFDIT
AARRYADFAVKARAAGRGFPTPDGYIAAIAASKGFAVATRDTSAFDAAGVEVINPWAASTA
Download Length: 426 bp
>T46018 NZ_CP007046:556557-556982 [Rhizobium leguminosarum bv. trifolii WSM1689]
ATGATTATCGTCGATACGAACGTCGTTTCCGAAGCGATGAAACCAGCGCCCGACGAAGCCGTGAAATTCTGGCTCGATGA
GCAGGCAGCCGAAACCCTCTTCCTTTCTAGCGTCACGATCGCCGAATTGATGTTTGGAATCGGCGCCCTCCCGGCTGGCA
AACGCAAGGAAAGGCTCTCCGACGCGTTGGACGGTCTGATGGAACTCTTCGAAAGCCGTATTTTGGCTTTCGACATCACA
GCGGCACGGCGCTATGCCGATTTCGCGGTCAAGGCCCGAGCCGCTGGCAGAGGATTTCCCACTCCGGACGGCTATATCGC
CGCCATCGCGGCATCAAAAGGGTTCGCCGTAGCCACGCGCGATACAAGTGCTTTCGACGCTGCAGGTGTTGAAGTGATCA
ATCCCTGGGCGGCTTCGACCGCATAA
ATGATTATCGTCGATACGAACGTCGTTTCCGAAGCGATGAAACCAGCGCCCGACGAAGCCGTGAAATTCTGGCTCGATGA
GCAGGCAGCCGAAACCCTCTTCCTTTCTAGCGTCACGATCGCCGAATTGATGTTTGGAATCGGCGCCCTCCCGGCTGGCA
AACGCAAGGAAAGGCTCTCCGACGCGTTGGACGGTCTGATGGAACTCTTCGAAAGCCGTATTTTGGCTTTCGACATCACA
GCGGCACGGCGCTATGCCGATTTCGCGGTCAAGGCCCGAGCCGCTGGCAGAGGATTTCCCACTCCGGACGGCTATATCGC
CGCCATCGCGGCATCAAAAGGGTTCGCCGTAGCCACGCGCGATACAAGTGCTTTCGACGCTGCAGGTGTTGAAGTGATCA
ATCCCTGGGCGGCTTCGACCGCATAA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9347.67 Da Isoelectric Point: 10.6531
>AT46018 WP_025397318.1 NZ_CP007046:556306-556560 [Rhizobium leguminosarum bv. trifolii WSM1689]
MPAVTIRNLSDATHRALKVRAAHHGRSAEAEMREILEAAVRPETRLRLGSALAERSRRLGLTNEDFAVLDQARDTLPAKP
MSFE
MPAVTIRNLSDATHRALKVRAAHHGRSAEAEMREILEAAVRPETRLRLGSALAERSRRLGLTNEDFAVLDQARDTLPAKP
MSFE
Download Length: 255 bp
>AT46018 NZ_CP007046:556306-556560 [Rhizobium leguminosarum bv. trifolii WSM1689]
ATGCCCGCAGTCACAATCAGAAACCTCTCCGACGCGACGCACCGTGCTCTCAAGGTGCGTGCGGCTCATCACGGGCGCAG
CGCCGAAGCGGAAATGCGCGAAATCCTCGAGGCTGCCGTCCGTCCGGAAACACGCCTGCGTCTTGGCAGCGCGCTCGCCG
AACGGAGCCGTCGCCTCGGGTTGACGAATGAGGACTTTGCCGTTCTGGACCAAGCTCGCGACACATTGCCTGCAAAGCCG
ATGAGCTTTGAATGA
ATGCCCGCAGTCACAATCAGAAACCTCTCCGACGCGACGCACCGTGCTCTCAAGGTGCGTGCGGCTCATCACGGGCGCAG
CGCCGAAGCGGAAATGCGCGAAATCCTCGAGGCTGCCGTCCGTCCGGAAACACGCCTGCGTCTTGGCAGCGCGCTCGCCG
AACGGAGCCGTCGCCTCGGGTTGACGAATGAGGACTTTGCCGTTCTGGACCAAGCTCGCGACACATTGCCTGCAAAGCCG
ATGAGCTTTGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|