Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1871290..1871524 | Replicon | chromosome |
| Accession | NZ_CP007037 | ||
| Organism | Shigella flexneri G1663 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1871291..1871394 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1871290..1871524 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SF2A_RS10255 | 1866712..1867179 | - | 468 | Protein_1874 | DNA-binding transcriptional regulator PgrR | - |
| SF2A_RS10260 | 1867243..1867553 | + | 311 | Protein_1875 | transposase | - |
| SF2A_RS27470 | 1867596..1868805 | - | 1210 | Protein_1876 | IS3 family transposase | - |
| SF2A_RS10280 | 1868860..1869708 | + | 849 | Protein_1877 | IS3-like element IS600 family transposase | - |
| SF2A_RS27475 | 1869825..1870106 | + | 282 | WP_005127484.1 | excisionase | - |
| SF2A_RS30840 | 1870072..1871149 | + | 1078 | Protein_1879 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1871290..1871524 | + | 235 | - | - | Antitoxin |
| - | 1871291..1871394 | - | 104 | - | - | Toxin |
| SF2A_RS10295 | 1871552..1871893 | - | 342 | WP_000976476.1 | YebY family protein | - |
| SF2A_RS27490 | 1871906..1872778 | - | 873 | Protein_1881 | copper homeostasis membrane protein CopD | - |
| SF2A_RS10310 | 1872782..1873156 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| SF2A_RS10315 | 1873295..1873525 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| SF2A_RS10320 | 1873627..1874283 | + | 657 | Protein_1884 | carbon-nitrogen hydrolase family protein | - |
| SF2A_RS10325 | 1874307..1874969 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 / flhA / flhA | 1867243..1948036 | 80793 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T45976 NZ_CP007037:c1871394-1871291 [Shigella flexneri G1663]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT45976 NZ_CP007037:1871290-1871524 [Shigella flexneri G1663]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
