Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1035351..1035938 Replicon chromosome
Accession NZ_CP007035
Organism Niabella soli DSM 19437

Toxin (Protein)


Gene name PumA Uniprot ID W0EV65
Locus tag NIASO_RS04335 Protein ID WP_025298701.1
Coordinates 1035351..1035650 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID W0F020
Locus tag NIASO_RS04340 Protein ID WP_008583186.1
Coordinates 1035654..1035938 (+) Length 95 a.a.

Genomic Context

NIASO_RS04315NIASO_RS04325NIASO_RS04330NIASO_RS04335NIASO_RS04340NIASO_RS04355NIASO_RS04360NIASO_RS04365NIASO_RS04320NIASO_RS04345NIASO_RS04350
Location: 1031107..1032156 (1050 bp)
Type: Others
Protein ID: WP_008583195.1
Location: 1032656..1034011 (1356 bp)
Type: Others
Protein ID: WP_044046275.1
Location: 1034129..1035097 (969 bp)
Type: Others
Protein ID: WP_008583189.1
Location: 1035351..1035650 (300 bp)
Type: Toxin
Protein ID: WP_025298701.1
Location: 1035654..1035938 (285 bp)
Type: Antitoxin
Protein ID: WP_008583186.1
Location: 1038721..1039716 (996 bp)
Type: Others
Protein ID: WP_008583181.1
Location: 1039741..1040439 (699 bp)
Type: Others
Protein ID: WP_008583179.1
Location: 1040439..1040915 (477 bp)
Type: Others
Protein ID: WP_008583177.1
Location: 1032218..1032499 (282 bp)
Type: Others
Protein ID: WP_008583193.1
Location: 1035977..1037104 (1128 bp)
Type: Others
Protein ID: WP_008583184.1
Location: 1037161..1038243 (1083 bp)
Type: Others
Protein ID: WP_052356611.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NIASO_RS043151031107..1032156+1050WP_008583195.1ABC transporter permease-
NIASO_RS043201032218..1032499-282WP_008583193.1DUF721 domain-containing protein-
NIASO_RS043251032656..1034011+1356WP_044046275.1hypothetical protein-
NIASO_RS043301034129..1035097+969WP_008583189.1peptidoglycan DD-metalloendopeptidase family protein-
NIASO_RS043351035351..1035650+300WP_025298701.1type II toxin-antitoxin system RelE/ParE family toxinToxin
NIASO_RS043401035654..1035938+285WP_008583186.1putative addiction module antidote proteinAntitoxin
NIASO_RS043451035977..1037104-1128WP_008583184.1DUF1624 domain-containing protein-
NIASO_RS043501037161..1038243-1083WP_052356611.1DNA replication and repair protein RecF-
NIASO_RS043551038721..1039716+996WP_008583181.1pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha-
NIASO_RS043601039741..1040439+699WP_008583179.1tetratricopeptide repeat protein-
NIASO_RS043651040439..1040915+477WP_008583177.16,7-dimethyl-8-ribityllumazine synthase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-93)

Antitoxin

Uncharacterized protein HI1420

(3-89)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11811.84 Da        Isoelectric Point: 10.2169

>T45969 WP_025298701.1 NZ_CP007035:1035351-1035650 [Niabella soli DSM 19437]
MYFIEKTIEFDKWLRKLRDLRAKAKILFRIQKLENEEHFGDCKSVGNGINELKINYSKGYRIYFKETNGKIIILLIGGDK
SSQQKDIEKAKEIWEKLKK

Download         Length: 300 bp

>T45969 NZ_CP007035:1035351-1035650 [Niabella soli DSM 19437]
ATGTACTTTATTGAAAAAACCATAGAATTTGACAAATGGCTGAGGAAATTGAGGGACTTACGTGCAAAAGCAAAAATTTT
GTTTAGAATTCAAAAATTGGAAAATGAAGAACATTTTGGCGATTGTAAATCTGTTGGAAATGGAATTAATGAATTGAAAA
TTAACTATTCGAAAGGTTATAGAATCTATTTCAAAGAAACAAATGGGAAAATTATCATTTTGCTCATCGGAGGAGACAAA
TCGAGCCAGCAGAAAGACATTGAAAAAGCAAAAGAAATTTGGGAAAAATTGAAGAAATAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10111.61 Da        Isoelectric Point: 4.5960

>AT45969 WP_008583186.1 NZ_CP007035:1035654-1035938 [Niabella soli DSM 19437]
METSKFDIADYLDSNETIAEYLNVLLEEGNESEIIAGIGHIAKAIGMTKIAEETGLSRPSLYKALSEGARPQFSTIMKIL
KAVGGQIRIAPISA

Download         Length: 285 bp

>AT45969 NZ_CP007035:1035654-1035938 [Niabella soli DSM 19437]
ATGGAAACCTCAAAATTTGATATTGCAGATTATTTAGATAGCAATGAGACGATTGCTGAATATCTTAATGTACTTTTAGA
AGAAGGAAACGAGTCTGAAATAATTGCAGGAATCGGGCATATCGCAAAAGCGATAGGAATGACTAAAATTGCTGAAGAAA
CAGGGCTTAGCCGGCCAAGCTTATACAAAGCCTTATCTGAAGGTGCCAGGCCTCAGTTTTCAACAATAATGAAAATTTTG
AAAGCCGTAGGCGGGCAAATCAGAATAGCTCCCATATCTGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBW0EV65

Antitoxin

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Source
ID
Structure
AlphaFold DBW0F020

References