Detailed information of TA system TA045957

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 3557732..3558463
• Replicon: chromosome
• Accession: NZ_CP007029
• Organism: Thioalkalivibrio paradoxus ARh

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: THITH_RS16100
• Protein ID: WP_006746776.1
• Coordinates: 3557732..3558208 (-)
• Length: 159 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: W0DM32
• Locus tag: THITH_RS16105
• Protein ID: WP_006746775.1
• Coordinates: 3558209..3558463 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-126)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 159 a.a.
• Molecular weight: 17233.76 Da
• Isoelectric Point: 7.1652

>T45957 WP_006746776.1 NZ_CP007029:c3558208-3557732 [Thioalkalivibrio paradoxus ARh 1]
MIVLDTNVVFEAMRPEPDATVRAWLNDQAAGTLYLSSVPLAELLFGIRALPAGKRKNLLDRALTELLELFKNRVLPFDTD
AARHYADLTVTARNGGRGFPTPDGYIAAIAASKGFIVASRDTSPYEASGVTVINPWGAMTERYANCHGQRPPPMMKEA

Nucleotide

• Length: 477 bp

>T45957 NZ_CP007029:c3558208-3557732 [Thioalkalivibrio paradoxus ARh 1]
ATGATTGTCCTGGATACCAACGTCGTTTTCGAGGCGATGAGGCCGGAGCCGGACGCGACCGTGAGGGCTTGGCTGAACGA
CCAGGCGGCCGGGACCTTGTACCTGTCCAGCGTCCCCCTGGCCGAGTTGCTGTTCGGCATCCGGGCGTTGCCAGCGGGAA
AGCGCAAGAACCTGCTCGATCGCGCCCTGACCGAGCTGCTGGAGCTGTTCAAGAATCGGGTCTTGCCGTTCGACACCGAT
GCAGCGCGCCACTATGCCGACCTGACCGTGACAGCCAGAAACGGCGGGCGCGGCTTTCCGACGCCGGACGGCTACATCGC
GGCCATTGCCGCATCGAAAGGATTCATTGTGGCATCACGAGACACCTCGCCCTATGAAGCGTCTGGCGTGACCGTCATCA
ACCCTTGGGGGGCGATGACCGAACGCTACGCTAACTGTCATGGCCAGCGGCCACCCCCGATGATGAAAGAGGCGTAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9265.57 Da
• Isoelectric Point: 8.8736

>AT45957 WP_006746775.1 NZ_CP007029:c3558463-3558209 [Thioalkalivibrio paradoxus ARh 1]
MAILTVRNVPDDVHRALRVRAAQHGRSTEAEVREILATAVNPEKRVRVSEALAAIGRKIGLTDDDFAVFESVRDKTPAKP
LSFD

Nucleotide

• Length: 255 bp

>AT45957 NZ_CP007029:c3558463-3558209 [Thioalkalivibrio paradoxus ARh 1]
ATGGCGATCCTGACTGTAAGGAACGTGCCTGATGACGTGCACCGCGCTTTGCGCGTGCGGGCGGCTCAACACGGCCGCAG
CACGGAAGCCGAGGTGCGCGAGATTCTGGCAACCGCGGTCAATCCGGAGAAGCGCGTGCGCGTGAGCGAGGCCCTGGCCG
CCATCGGCCGCAAGATCGGTCTGACCGACGATGATTTCGCCGTCTTCGAGAGTGTGCGCGACAAGACGCCGGCCAAACCG
TTGAGCTTCGACTGA

Structures

Antitoxin

• AlphaFold DB: W0DM32