Detailed information of TA system TA045848

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 3834584..3835097
• Replicon: chromosome
• Accession: NZ_CP007014
• Organism: Pseudomonas syringae CC1557

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: N018_RS26670
• Protein ID: WP_080274862.1
• Coordinates: 3834813..3835097 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: W0MTF7
• Locus tag: N018_RS16885
• Protein ID: WP_024647622.1
• Coordinates: 3834584..3834823 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N018_RS16865	3830704..3831489	+	786	WP_025390287.1	membrane protein	-
N018_RS16870	3831653..3832561	-	909	WP_024647625.1	DUF808 domain-containing protein	-
N018_RS16875	3832709..3833215	-	507	WP_025390288.1	winged helix-turn-helix transcriptional regulator	-
N018_RS16880	3833397..3834413	+	1017	WP_024647623.1	1-aminocyclopropane-1-carboxylate deaminase	-
N018_RS16885	3834584..3834823	+	240	WP_024647622.1	CopG family ribbon-helix-helix protein	Antitoxin
N018_RS26670	3834813..3835097	+	285	WP_080274862.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
N018_RS16890	3835134..3835988	-	855	WP_025390289.1	LysR family transcriptional regulator	-
N018_RS16895	3836063..3837019	+	957	WP_024647620.1	DMT family transporter	-
N018_RS16900	3837038..3837442	-	405	WP_024647619.1	hypothetical protein	-
N018_RS16905	3837592..3839520	-	1929	WP_024647618.1	methyl-accepting chemotaxis protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-89)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-41)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10739.46 Da
• Isoelectric Point: 10.1524

>T45848 WP_080274862.1 NZ_CP007014:3834813-3835097 [Pseudomonas syringae CC1557]
MHVEWLKTALKNLDDEAAYLSLENPAAAAAFVEAIQSSVNQLARFPAMGREGRIAGTREWPLPDLPYLIPYRIRSGRLQV
LRIFHTRRLPPSLW

Nucleotide

• Length: 285 bp

>T45848 NZ_CP007014:3834813-3835097 [Pseudomonas syringae CC1557]
ATGCACGTTGAATGGCTAAAGACTGCGCTGAAAAATCTGGATGATGAGGCAGCCTACCTATCATTGGAAAATCCGGCTGC
CGCAGCCGCTTTCGTTGAAGCAATACAATCAAGCGTCAATCAGCTCGCACGCTTCCCTGCAATGGGCCGGGAAGGACGCA
TTGCAGGGACAAGAGAATGGCCTCTGCCAGACCTGCCTTACTTGATTCCTTATCGAATCCGTAGCGGCCGATTACAAGTT
CTGCGGATATTCCACACAAGGAGACTTCCACCCTCACTGTGGTAG

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8882.01 Da
• Isoelectric Point: 4.6258

>AT45848 WP_024647622.1 NZ_CP007014:3834584-3834823 [Pseudomonas syringae CC1557]
MSVMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFASEEEVKSVVNKWTNNAR

Nucleotide

• Length: 240 bp

>AT45848 NZ_CP007014:3834584-3834823 [Pseudomonas syringae CC1557]
ATGTCCGTTATGTCTCTACGCCTGCCGGACGAGATGGCAGATACCCTCGCACATCTTGCCAAAGCGACCGGGCGCAGCAA
GTCTTTCCTGGCGCTGGATGCACTGCGTGAATACCTGACTCGCGAAGCCTGGCAGATCGCCGAAATTCAGCGTGCGATTG
AAGAAGCTGATGCTGGCGAGTTCGCAAGCGAAGAGGAAGTGAAGTCCGTTGTAAATAAATGGACGAACAATGCACGTTGA

Structures

Antitoxin

• AlphaFold DB: W0MTF7