Detailed information of TA system TA045845

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 3567733..3568616
• Replicon: chromosome
• Accession: NZ_CP007012
• Organism: Pseudomonas sp. FGI182

Toxin (Protein)

• Gene name: -
• Uniprot ID: V9X1L0
• Locus tag: C163_RS15715
• Protein ID: WP_025339649.1
• Coordinates: 3567733..3568170 (-)
• Length: 146 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: F8G488
• Locus tag: C163_RS15720
• Protein ID: WP_013973163.1
• Coordinates: 3568167..3568616 (-)
• Length: 150 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C163_RS15695	3562884..3563948	+	1065	WP_025339646.1	TerC family protein	-
C163_RS15700	3564080..3565309	-	1230	WP_013973159.1	acyl-CoA dehydrogenase	-
C163_RS15705	3565450..3566376	+	927	WP_025339647.1	LysR family transcriptional regulator	-
C163_RS15710	3566571..3567725	+	1155	WP_025339648.1	aminotransferase class V-fold PLP-dependent enzyme	-
C163_RS15715	3567733..3568170	-	438	WP_025339649.1	RES family NAD+ phosphorylase	Toxin
C163_RS15720	3568167..3568616	-	450	WP_013973163.1	DUF2384 domain-containing protein	Antitoxin
C163_RS15725	3568767..3569420	-	654	WP_025339650.1	oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB	-
C163_RS15730	3569525..3570448	+	924	WP_025339651.1	LysR family transcriptional regulator	-
C163_RS15735	3570496..3571326	+	831	WP_025339652.1	AraC family transcriptional regulator	-
C163_RS15740	3571377..3571961	+	585	WP_025339653.1	LysE family translocator	-
C163_RS15745	3572134..3573333	-	1200	WP_025339654.1	sugar transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-137)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (33-91)

Sequences

Toxin

Protein

• Length: 146 a.a.
• Molecular weight: 15968.25 Da
• Isoelectric Point: 6.2202

>T45845 WP_025339649.1 NZ_CP007012:c3568170-3567733 [Pseudomonas sp. FGI182]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSSQTELTRGLGNRFLDECSALLLPVPSAIMPSTTNYLFNPRHPQANSARLKVEDFTPDSRLF

Nucleotide

• Length: 438 bp

>T45845 NZ_CP007012:c3568170-3567733 [Pseudomonas sp. FGI182]
GTGATTCTGTGGCGTATCAGCGCCTATGCAGACTTGAGCGGAACGGGCGGTTTGCGTGTCAGCGGCCGCTGGCACCAGGC
GGGCCGGCCAGTGGTGTATGCCGCCACCAGCCCAGCCGGGGCAATGCTGGAGGTGCTGGTGCACCTGGAGATCGACCCTG
AGGATTTCCCCACCACCATGCGGCTGCTGCGTATCGAGTTGCCCGATACCGTTTCGCAAGCGCAGTTGCCCGCCTTGCAG
CCTGGCTGGTCGAGCCAGACCGAACTGACCCGGGGCCTGGGCAACCGCTTTCTGGATGAGTGCTCGGCATTGCTGTTGCC
GGTGCCGAGCGCGATCATGCCCAGCACCACCAATTACCTGTTCAACCCGCGCCATCCGCAGGCAAACAGCGCCAGGCTCA
AGGTCGAGGACTTCACCCCGGACAGCCGGCTGTTCTAG

Antitoxin

Protein

• Length: 150 a.a.
• Molecular weight: 17004.59 Da
• Isoelectric Point: 6.3405

>AT45845 WP_013973163.1 NZ_CP007012:c3568616-3568167 [Pseudomonas sp. FGI182]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL

Nucleotide

• Length: 450 bp

>AT45845 NZ_CP007012:c3568616-3568167 [Pseudomonas sp. FGI182]
ATGCTTGCCGAAGTGCTTCGCGACAACGGTTACCACGAGTACCGGGCGCGCCTGCATGCACTGCTGGAAATCCCCGAACT
CGCCAGTGACTTCGAAATCCACACCCGCATCACCCATGGCTTCGCTGCCACCTGGCTGGTGAAACTGACCGAGCTCGGCG
TGTTCACCCCTGTGGAGCGTGACCAGATCATTCCCCTGCGCACGCTGAAAACCCGCATTGAACGCGACCAGCCACTGACC
GTGGAAGAAAGCGACCGGCTGTTCCGTTCGGCCCATATCACCGCCATGGCCGAAGCCGTGTTCGGTGAGGCGGGCAAGGC
CAAGCGCTGGCTGTCCAAGCCCAAGGAGCGCTTCTCGGGGCTGACGCCGATGCAGATGCTCACCACCCAGCAGGGCACCA
CCCAGGTCGAAGAGATGTTGCTGCAGATCGCCGAGGGCTTCGGCCTGTGA

Structures

Toxin

• AlphaFold DB: V9X1L0

Antitoxin

• AlphaFold DB: F8G488