Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-higA/HigB-HigA
Location 294024..294897 Replicon chromosome
Accession NZ_CP007012
Organism Pseudomonas sp. FGI182

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C163_RS01275 Protein ID WP_081742214.1
Coordinates 294024..294377 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag C163_RS01280 Protein ID WP_025337351.1
Coordinates 294424..294897 (+) Length 158 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C163_RS01260 290330..291049 - 720 WP_025337347.1 response regulator -
C163_RS01265 291190..293487 + 2298 WP_025337348.1 TonB-dependent siderophore receptor -
C163_RS01270 293640..293846 - 207 WP_025337349.1 DUF3079 domain-containing protein -
C163_RS01275 294024..294377 + 354 WP_081742214.1 type II toxin-antitoxin system HigB family toxin Toxin
C163_RS01280 294424..294897 + 474 WP_025337351.1 transcriptional regulator Antitoxin
C163_RS26070 295282..295734 - 453 WP_081742215.1 hypothetical protein -
C163_RS01290 295926..296111 - 186 Protein_248 XRE family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 293640..306660 13020


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(73-111)

Antitoxin

Antitoxin HigA

(43-154)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13678.86 Da        Isoelectric Point: 10.4174

>T45844 WP_081742214.1 NZ_CP007012:294024-294377 [Pseudomonas sp. FGI182]
MRVITKAAVTKAIEAHAQWKAPLSLWLTTFDRATLRFESFEQLRNTWSTAFSWNVDRIPCSKLRPSSRKGPLDVYVFDIK
KNECRLIAWLNTRTGTLYIKAILSHAEYDKWCKSDVR

Download         Length: 354 bp

>T45844 NZ_CP007012:294024-294377 [Pseudomonas sp. FGI182]
ATGCGGGTGATAACGAAAGCGGCGGTTACCAAAGCCATCGAAGCTCACGCCCAGTGGAAAGCCCCCCTGAGCCTGTGGCT
CACGACCTTTGATAGGGCGACGCTGCGCTTCGAGTCTTTTGAGCAGCTAAGGAATACGTGGTCTACCGCCTTTAGCTGGA
ACGTTGACCGCATTCCTTGTTCAAAACTCAGGCCCTCCAGCCGAAAAGGGCCGCTTGATGTCTATGTGTTCGATATCAAG
AAAAACGAATGCCGTCTGATCGCATGGCTCAACACACGAACGGGCACCCTCTATATCAAAGCCATTCTGTCGCACGCGGA
GTACGACAAGTGGTGCAAGAGCGATGTCAGGTAG

Antitoxin


Download         Length: 158 a.a.        Molecular weight: 17228.68 Da        Isoelectric Point: 4.5725

>AT45844 WP_025337351.1 NZ_CP007012:294424-294897 [Pseudomonas sp. FGI182]
MKRDKIEANGLDAFIANISPMLDGLNAQMATMAQLLAACHDPIKDDAELQARMALIDELYSHADSESHAAARFAEMVADR
VYEYESESVLVPFASQAEALAFLLSDRGVKQKDLASIATQSAVSEILNNKRKMTVAQIKGFAEFFSVPVEFFMHGVV

Download         Length: 474 bp

>AT45844 NZ_CP007012:294424-294897 [Pseudomonas sp. FGI182]
ATGAAGCGGGATAAAATCGAAGCCAATGGACTAGATGCCTTCATCGCTAATATCTCACCCATGCTGGATGGCCTGAACGC
CCAGATGGCAACCATGGCCCAGCTTCTTGCTGCCTGCCATGACCCTATCAAGGACGATGCAGAGCTCCAGGCGCGGATGG
CATTGATCGATGAGCTCTACTCGCATGCCGACAGCGAAAGTCACGCAGCAGCGCGCTTTGCGGAGATGGTGGCGGATCGT
GTCTACGAGTATGAGAGTGAGTCGGTACTCGTGCCGTTTGCGAGCCAGGCCGAAGCGTTGGCCTTCCTGCTGTCGGACAG
GGGCGTGAAGCAGAAGGACCTTGCCTCGATAGCAACTCAGAGCGCGGTTTCAGAGATTTTGAACAACAAGCGGAAGATGA
CGGTTGCCCAGATAAAGGGCTTTGCTGAGTTTTTCAGCGTACCGGTTGAGTTTTTCATGCATGGGGTGGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References