Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 327990..328588 Replicon chromosome
Accession NZ_CP007003
Organism Trueperella pyogenes TP8

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag X956_RS01465 Protein ID WP_039661772.1
Coordinates 328274..328588 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag X956_RS01460 Protein ID WP_024963631.1
Coordinates 327990..328283 (-) Length 98 a.a.

Genomic Context

X956_RS01435X956_RS01440X956_RS01445X956_RS10415X956_RS01475X956_RS01495X956_RS01430X956_RS01455X956_RS01460X956_RS01465X956_RS01480X956_RS01485X956_RS10860
Location: 324151..325365 (1215 bp)
Type: Others
Protein ID: WP_039661762.1
Location: 325425..326444 (1020 bp)
Type: Others
Protein ID: WP_039661764.1
Location: 326441..327067 (627 bp)
Type: Others
Protein ID: WP_039661770.1
Location: 328918..329766 (849 bp)
Type: Others
Protein ID: WP_196246951.1
Location: 330094..330450 (357 bp)
Type: Others
Protein ID: WP_039661774.1
Location: 332707..333555 (849 bp)
Type: Others
Protein ID: WP_172463151.1
Location: 323420..324067 (648 bp)
Type: Others
Protein ID: WP_039661760.1
Location: 327467..327883 (417 bp)
Type: Others
Protein ID: WP_039661771.1
Location: 327990..328283 (294 bp)
Type: Antitoxin
Protein ID: WP_024963631.1
Location: 328274..328588 (315 bp)
Type: Toxin
Protein ID: WP_039661772.1
Location: 330582..331193 (612 bp)
Type: Others
Protein ID: WP_039663456.1
Location: 331337..332290 (954 bp)
Type: Others
Protein ID: WP_039661776.1
Location: 332287..332529 (243 bp)
Type: Others
Protein ID: WP_024963636.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
X956_RS01430323420..324067-648WP_039661760.15-formyltetrahydrofolate cyclo-ligase-
X956_RS01435324151..325365+1215WP_039661762.1molybdopterin molybdotransferase MoeA-
X956_RS01440325425..326444+1020WP_039661764.1hypothetical protein-
X956_RS01445326441..327067+627WP_039661770.1alpha/beta fold hydrolase-
X956_RS01455327467..327883-417WP_039661771.1SRPBCC family protein-
X956_RS01460327990..328283-294WP_024963631.1putative addiction module antidote proteinAntitoxin
X956_RS01465328274..328588-315WP_039661772.1type II toxin-antitoxin system RelE/ParE family toxinToxin
X956_RS10415328918..329766+849WP_196246951.1siderophore-interacting protein-
X956_RS01475330094..330450+357WP_039661774.1hypothetical protein-
X956_RS01480330582..331193-612WP_039663456.1alpha/beta hydrolase-
X956_RS01485331337..332290-954WP_039661776.1SRPBCC family protein-
X956_RS10860332287..332529-243WP_024963636.1hypothetical protein-
X956_RS01495332707..333555+849WP_172463151.1ABC transporter substrate-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--327990..34038412394


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-97)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11958.94 Da        Isoelectric Point: 10.1896

>T45842 WP_039661772.1 NZ_CP007003:c328588-328274 [Trueperella pyogenes TP8]
VKIRQTDVYAHWFRKLKDVQDKVRINIALQRCKIAGEVVGDVKPVGDGVFEMRIHVGPGYRIYYMSRGNQLMLLVIGGDK
STQQRDITKVKQLATEIIREGSWE

Download         Length: 315 bp

>T45842 NZ_CP007003:c328588-328274 [Trueperella pyogenes TP8]
GTGAAGATTCGGCAAACCGACGTGTATGCTCACTGGTTTCGCAAGCTAAAAGATGTCCAGGACAAGGTCCGAATCAATAT
TGCACTTCAGCGTTGCAAAATAGCTGGCGAAGTAGTGGGTGACGTCAAGCCGGTTGGTGATGGCGTTTTTGAGATGCGAA
TTCACGTTGGCCCCGGCTATCGGATTTACTACATGTCAAGAGGGAACCAACTTATGCTACTAGTCATTGGTGGTGATAAG
TCCACCCAGCAGCGTGACATAACCAAAGTTAAACAGCTTGCAACAGAAATTATTAGGGAGGGATCATGGGAGTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10245.72 Da        Isoelectric Point: 4.5843

>AT45842 WP_024963631.1 NZ_CP007003:c328283-327990 [Trueperella pyogenes TP8]
MGVKISTWDASEYLETKEDIAAYLNAALEEGDPALLQVALGDVAKARGVTAIAREAGVGRESLYKSLSENGNPSWQTITK
VLTALGLKIEVKAIALA

Download         Length: 294 bp

>AT45842 NZ_CP007003:c328283-327990 [Trueperella pyogenes TP8]
ATGGGAGTAAAAATCAGCACCTGGGATGCCAGCGAATACCTTGAAACCAAGGAAGATATTGCTGCCTACCTGAACGCGGC
ACTCGAAGAGGGCGACCCGGCTCTCCTGCAGGTCGCACTTGGTGATGTCGCCAAAGCGCGTGGTGTGACCGCTATCGCGC
GAGAAGCCGGTGTTGGACGCGAGTCTCTCTACAAGTCGCTTTCCGAAAACGGCAATCCGTCCTGGCAGACCATCACAAAG
GTTCTCACTGCACTCGGGCTGAAGATCGAAGTCAAAGCCATTGCGTTAGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References