Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3061106..3061740 Replicon chromosome
Accession NZ_CP006929
Organism Dickeya zeae EC1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag W909_RS13505 Protein ID WP_038908605.1
Coordinates 3061336..3061740 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag W909_RS13500 Protein ID WP_039669118.1
Coordinates 3061106..3061336 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
W909_RS13485 3058462..3059582 + 1121 Protein_2662 IS3 family transposase -
W909_RS13490 3059777..3060073 - 297 WP_016941176.1 hypothetical protein -
W909_RS13500 3061106..3061336 + 231 WP_039669118.1 antitoxin Antitoxin
W909_RS13505 3061336..3061740 + 405 WP_038908605.1 tRNA(fMet)-specific endonuclease VapC Toxin
W909_RS13510 3062305..3063147 - 843 WP_016943414.1 VOC family protein -
W909_RS13515 3063181..3063900 - 720 WP_016943413.1 ABC transporter ATP-binding protein -
W909_RS13520 3063897..3064676 - 780 WP_016943412.1 ABC transporter ATP-binding protein -
W909_RS13525 3064673..3065560 - 888 WP_016943411.1 branched-chain amino acid ABC transporter permease -
W909_RS13530 3065553..3066446 - 894 WP_016943410.1 branched-chain amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15008.23 Da        Isoelectric Point: 7.9982

>T45787 WP_038908605.1 NZ_CP006929:3061336-3061740 [Dickeya zeae EC1]
MLKYLLDTNICIYTIKNKPQEVREAFQRYYGQFAISAITLMELIYGAEKSANPEKNLAVIEGFSARLDIQSYGFDAAVHT
GQIRAELAKQGTPIGPYDAMLAGHARSAGLILITNNVREFERVPGLRVENWVSR

Download         Length: 405 bp

>T45787 NZ_CP006929:3061336-3061740 [Dickeya zeae EC1]
ATGTTGAAATACCTGCTTGATACCAACATTTGCATTTACACCATAAAGAACAAGCCGCAAGAGGTCAGAGAGGCGTTTCA
GCGTTATTACGGGCAGTTTGCGATCAGTGCCATCACGTTGATGGAGCTTATCTATGGCGCGGAAAAGTCGGCCAATCCAG
AAAAGAATCTGGCGGTAATAGAAGGATTTTCCGCACGTCTGGACATCCAGTCCTATGGGTTTGATGCTGCCGTGCATACC
GGTCAAATTCGTGCCGAGCTGGCGAAACAAGGAACCCCCATAGGCCCGTATGATGCCATGTTAGCCGGTCACGCACGATC
CGCAGGTTTAATACTGATAACAAACAATGTACGCGAATTTGAGCGTGTACCTGGGCTACGAGTGGAAAACTGGGTAAGCC
GATAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8677.68 Da        Isoelectric Point: 4.5580

>AT45787 WP_039669118.1 NZ_CP006929:3061106-3061336 [Dickeya zeae EC1]
MEKTTVFKSNRSQAVRLPKAVALPDDVRHVDIVAIGRTRIITPAGESWDSWFDEASVTPDFMSTREQPDEQIRDDF

Download         Length: 231 bp

>AT45787 NZ_CP006929:3061106-3061336 [Dickeya zeae EC1]
ATGGAAAAAACCACAGTATTTAAAAGCAATCGCAGCCAGGCGGTACGACTCCCTAAAGCTGTTGCGTTACCCGATGATGT
TAGGCATGTCGATATTGTCGCCATTGGCCGCACGCGTATCATTACTCCGGCAGGCGAAAGCTGGGACAGTTGGTTTGATG
AAGCGAGCGTGACACCGGATTTCATGAGCACCAGAGAGCAACCGGATGAACAGATCAGGGACGATTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References