Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 1583071..1583821 Replicon chromosome
Accession NZ_CP006929
Organism Dickeya zeae EC1

Toxin (Protein)


Gene name dhiT Uniprot ID -
Locus tag W909_RS06945 Protein ID WP_016943626.1
Coordinates 1583071..1583328 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID -
Locus tag W909_RS06950 Protein ID WP_016943627.1
Coordinates 1583336..1583821 (+) Length 162 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
W909_RS06935 1579786..1581936 - 2151 WP_016943623.1 formate dehydrogenase subunit alpha -
W909_RS06940 1581971..1582513 - 543 WP_016943624.1 4Fe-4S dicluster domain-containing protein -
W909_RS06945 1583071..1583328 + 258 WP_016943626.1 DUF4160 domain-containing protein Toxin
W909_RS06950 1583336..1583821 + 486 WP_016943627.1 addiction module antitoxin Antitoxin
W909_RS06955 1583910..1584419 - 510 WP_016943628.1 hydrogenase maturation peptidase HycI -
W909_RS06960 1584412..1584810 - 399 WP_016943629.1 formate hydrogenlyase maturation HycH family protein -
W909_RS06965 1584810..1585598 - 789 WP_016943630.1 NADH-quinone oxidoreductase subunit B family protein -
W909_RS06970 1585595..1586164 - 570 WP_016943631.1 hydrogenase 4 subunit H -
W909_RS06975 1586175..1587902 - 1728 WP_016943632.1 hydrogenase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-73)

Antitoxin

Uncharacterized protein HI1420

(80-156)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9839.45 Da        Isoelectric Point: 7.5565

>T45776 WP_016943626.1 NZ_CP006929:1583071-1583328 [Dickeya zeae EC1]
MPEIDRLAGLIFHLYFYDDERHHLPHVHVCYGNHELIISIRTGTEIEGYLPNTKRKLAIAHIMAHREQLLSMWAQAVIGK
NPGKL

Download         Length: 258 bp

>T45776 NZ_CP006929:1583071-1583328 [Dickeya zeae EC1]
ATGCCTGAGATTGACAGACTGGCAGGGTTAATCTTCCATCTGTACTTTTACGATGATGAGCGGCACCACTTGCCGCATGT
GCATGTCTGCTACGGCAATCATGAACTTATCATCAGTATTCGTACCGGAACCGAGATAGAGGGATATCTGCCAAATACCA
AACGTAAGCTGGCGATTGCACATATCATGGCGCATCGTGAGCAATTGCTGAGTATGTGGGCACAGGCGGTCATCGGGAAG
AATCCGGGAAAATTGTGA

Antitoxin


Download         Length: 162 a.a.        Molecular weight: 17932.40 Da        Isoelectric Point: 6.9893

>AT45776 WP_016943627.1 NZ_CP006929:1583336-1583821 [Dickeya zeae EC1]
MHKIVDVDAIGDFSLRLTYDDGLIYDVNLYRYASYPVFLHASQFIRFGLLPDGSLEWPDITISSSALREKGTYVGHTLAV
RERNFADIISRAFYDAVIENRPEILQAALKIAVDKHGNSTVAKEAGAKSRTSLYKSLNKNTNVSLATVVSLAHTVLQLEE
K

Download         Length: 486 bp

>AT45776 NZ_CP006929:1583336-1583821 [Dickeya zeae EC1]
ATGCATAAGATTGTGGATGTTGACGCGATTGGCGATTTTTCGTTGCGTCTGACCTATGACGACGGCCTGATATACGACGT
TAACCTGTATCGCTATGCCTCATATCCTGTGTTTTTACATGCCAGCCAGTTTATCCGATTTGGGTTATTACCTGATGGTT
CGCTGGAATGGCCGGATATCACGATCTCTTCGTCCGCATTACGGGAAAAGGGAACATATGTTGGCCACACCTTGGCGGTG
AGGGAGCGGAATTTTGCCGATATTATCTCCCGAGCCTTCTATGATGCCGTGATTGAGAACCGGCCTGAAATTCTGCAGGC
GGCACTGAAAATCGCAGTAGACAAACATGGCAACAGTACGGTGGCCAAAGAAGCGGGAGCCAAGAGCCGTACCAGCTTGT
ATAAATCGCTGAATAAAAATACTAATGTCAGCCTGGCGACGGTAGTTAGCCTGGCCCACACCGTGTTGCAACTGGAAGAG
AAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References