Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 694829..695507 Replicon chromosome
Accession NZ_CP006929
Organism Dickeya zeae EC1

Toxin (Protein)


Gene name cptA Uniprot ID D2BSA8
Locus tag W909_RS03215 Protein ID WP_012883372.1
Coordinates 695076..695507 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A2K9QKF2
Locus tag W909_RS03210 Protein ID WP_016943577.1
Coordinates 694829..695095 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
W909_RS03195 691980..692588 - 609 WP_016943574.1 HD domain-containing protein -
W909_RS03200 692801..693451 + 651 WP_016943575.1 hemolysin III family protein -
W909_RS03205 693539..694519 - 981 WP_016943576.1 tRNA-modifying protein YgfZ -
W909_RS03210 694829..695095 + 267 WP_016943577.1 FAD assembly factor SdhE Antitoxin
W909_RS03215 695076..695507 + 432 WP_012883372.1 protein YgfX Toxin
W909_RS03220 695596..696114 - 519 WP_016943578.1 flavodoxin FldB -
W909_RS03225 696291..697616 - 1326 WP_029456611.1 MHS family MFS transporter -
W909_RS03230 697880..698779 + 900 WP_016943580.1 site-specific tyrosine recombinase XerD -
W909_RS03235 698866..699582 + 717 WP_016943581.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 16887.54 Da        Isoelectric Point: 11.5023

>T45774 WP_012883372.1 NZ_CP006929:695076-695507 [Dickeya zeae EC1]
VAQWQCDLRVSWRMQLFSLLTHGFLMLMILLAPWPDGYAPLWLGLVTLVVFDFVRSQRSIKSRQGEISLRGDNQLHWQQR
DWQIVRRPWFMRNGVLLSLRAVDGKGQQRLWLASDSMGSEEWRLLRQQLQQPALHGTESSRHH

Download         Length: 432 bp

>T45774 NZ_CP006929:695076-695507 [Dickeya zeae EC1]
GTGGCCCAGTGGCAATGTGATTTACGCGTATCCTGGCGCATGCAGTTGTTTTCGCTGCTAACGCACGGATTTCTGATGCT
GATGATCCTGCTGGCTCCCTGGCCGGACGGCTACGCACCGCTGTGGCTCGGGTTAGTGACGCTGGTCGTGTTTGACTTTG
TGCGCAGCCAGCGAAGCATCAAATCGCGCCAGGGGGAGATTTCCCTGCGTGGCGATAATCAACTGCACTGGCAGCAACGT
GACTGGCAGATTGTCCGGCGACCGTGGTTCATGCGTAACGGCGTATTGTTATCGCTACGTGCGGTGGATGGTAAAGGGCA
ACAGCGTTTGTGGCTGGCGTCAGACAGTATGGGGAGTGAGGAATGGCGGCTGTTACGTCAACAGCTGCAGCAGCCTGCGC
TGCATGGAACGGAATCTTCCCGCCATCATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10404.88 Da        Isoelectric Point: 5.5981

>AT45774 WP_016943577.1 NZ_CP006929:694829-695095 [Dickeya zeae EC1]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQQFIRLLQCDDPDLFNWLMNHGEPGDPGLKRMVSLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT45774 NZ_CP006929:694829-695095 [Dickeya zeae EC1]
ATGGACATCAATAACAAAGCACGTATTCACTGGGCGTGCAGGCGTGGAATGCGCGAACTGGACATCTCCATCATGCCGTT
TTTCGAGCATGAGTACGATACGCTGAGCGATGACGACAAACAGCAGTTTATTCGTCTGCTGCAGTGTGACGATCCCGACC
TGTTTAATTGGTTGATGAACCACGGCGAGCCGGGTGATCCCGGTTTGAAGCGGATGGTTTCCCTTATTCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K9QB06

Antitoxin

Source ID Structure
AlphaFold DB A0A2K9QKF2

References