Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 462574..463208 Replicon chromosome
Accession NZ_CP006929
Organism Dickeya zeae EC1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag W909_RS02100 Protein ID WP_033576633.1
Coordinates 462804..463208 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag W909_RS02095 Protein ID WP_033576634.1
Coordinates 462574..462804 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
W909_RS02080 457738..460122 + 2385 WP_016943953.1 dynamin family protein -
W909_RS02085 460119..461024 + 906 WP_016943954.1 hypothetical protein -
W909_RS02090 461021..462094 + 1074 WP_016943955.1 patatin-like phospholipase family protein -
W909_RS02095 462574..462804 + 231 WP_033576634.1 antitoxin Antitoxin
W909_RS02100 462804..463208 + 405 WP_033576633.1 tRNA(fMet)-specific endonuclease VapC Toxin
W909_RS02105 463289..463732 + 444 WP_016943280.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
W909_RS02110 463822..464622 + 801 WP_016943279.1 helix-turn-helix transcriptional regulator -
W909_RS02115 465006..466445 + 1440 WP_016943278.1 sensor domain-containing diguanylate cyclase -
W909_RS19885 466486..466620 - 135 Protein_412 SAM-dependent methyltransferase -
W909_RS02120 466905..467759 + 855 WP_016943277.1 pirin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 445905..471426 25521
- flank IS/Tn - - 457403..457603 200


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15016.30 Da        Isoelectric Point: 7.9968

>T45771 WP_033576633.1 NZ_CP006929:462804-463208 [Dickeya zeae EC1]
MLKYLLDTNICIYTIKNKPQEVREAFQRYYGQFAISSITLMELIYGAEKSANPEKNLAVIEGFSARLEIQPYGFDAAVHT
GQIRAELAKKGTPIGPYDAMLAGHARSAGLILVTNNVREFERVPGLRVENWLNP

Download         Length: 405 bp

>T45771 NZ_CP006929:462804-463208 [Dickeya zeae EC1]
ATGTTGAAATACCTGCTTGATACCAACATTTGCATTTACACCATAAAGAACAAGCCGCAAGAGGTCAGAGAGGCGTTCCA
GCGTTATTACGGGCAATTTGCGATAAGCTCCATCACGTTGATGGAGCTTATCTATGGCGCGGAAAAGTCGGCCAATCCAG
AAAAGAATCTGGCGGTAATAGAAGGATTTTCCGCACGTCTGGAGATCCAGCCCTATGGGTTTGATGCCGCCGTGCATACC
GGGCAAATCCGTGCCGAGCTGGCAAAAAAGGGAACGCCGATTGGCCCGTATGATGCGATGCTGGCAGGCCATGCGCGCTC
GGCAGGCTTGATACTGGTGACGAACAATGTCCGTGAGTTTGAGCGCGTGCCGGGGCTGCGTGTGGAGAACTGGCTTAACC
CATAG

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8647.66 Da        Isoelectric Point: 4.5580

>AT45771 WP_033576634.1 NZ_CP006929:462574-462804 [Dickeya zeae EC1]
MEKATVFKSNRSQAVRLPKAVALPDDVRHVDIVAIGRTRIITPAGESWDSWFDEASVTPDFMSTREQPDEQIRDDF

Download         Length: 231 bp

>AT45771 NZ_CP006929:462574-462804 [Dickeya zeae EC1]
ATGGAAAAAGCCACGGTATTTAAAAGCAACCGGAGCCAGGCAGTACGGCTCCCTAAAGCTGTTGCGTTACCCGATGATGT
TAGGCATGTCGATATTGTCGCCATTGGCCGCACGCGTATCATTACTCCGGCAGGCGAAAGCTGGGACAGTTGGTTTGATG
AAGCGAGCGTGACACCGGATTTCATGAGCACCAGAGAGCAACCGGATGAACAGATCAGGGACGATTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References