45769

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc-RelB
Location 116172..116782 Replicon chromosome
Accession NZ_CP006929
Organism Dickeya zeae EC1

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag W909_RS00490 Protein ID WP_016941533.1
Coordinates 116172..116564 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag W909_RS00495 Protein ID WP_016941532.1
Coordinates 116561..116782 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
W909_RS00465 111291..112631 - 1341 WP_016941538.1 type III PLP-dependent enzyme -
W909_RS00470 112624..112935 - 312 WP_016941537.1 hypothetical protein -
W909_RS00475 113579..114331 + 753 WP_016941536.1 LuxR family transcriptional regulator -
W909_RS00480 114297..114935 - 639 WP_016941535.1 acyl-homoserine-lactone synthase -
W909_RS00485 115514..115762 + 249 WP_162830907.1 DUF1471 domain-containing protein -
W909_RS00490 116172..116564 - 393 WP_016941533.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
W909_RS00495 116561..116782 - 222 WP_016941532.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
W909_RS00500 117191..118513 + 1323 WP_039669099.1 IS4 family transposase -
W909_RS00505 118560..119033 - 474 WP_016943502.1 GNAT family N-acetyltransferase -
W909_RS00510 119127..120362 - 1236 WP_016943501.1 hypothetical protein -
W909_RS19765 120390..120824 + 435 WP_016943500.1 hypothetical protein -
W909_RS00520 120821..121351 + 531 WP_016943499.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 117191..118513 1322


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-52)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14610.60 Da        Isoelectric Point: 6.2265

>T45769 WP_016941533.1 NZ_CP006929:c116564-116172 [Dickeya zeae EC1]
MIWVSAQEVIAFHARILQRLPGVAGMPDPDRAEALIYRVQNRTHDEGVTDIFELAATYWVAIARGHIFNDGNKRTAFFVA
ITFLYRNGIRIRDTDNTLENLTVEAATGGKTVDQLAQSLRDLVDNLIPTR

Download         Length: 393 bp

>T45769 NZ_CP006929:c116564-116172 [Dickeya zeae EC1]
ATGATATGGGTCAGCGCACAGGAAGTTATCGCTTTCCATGCCCGTATTTTACAACGACTTCCCGGCGTTGCTGGCATGCC
CGACCCGGATAGAGCCGAAGCACTCATCTATCGGGTACAAAACCGCACGCACGACGAAGGCGTTACAGATATTTTTGAGC
TCGCCGCTACCTACTGGGTTGCTATTGCTCGTGGGCACATTTTTAATGATGGCAATAAACGCACGGCGTTCTTTGTAGCT
ATAACGTTTCTCTACCGCAACGGCATCCGCATTCGTGATACCGACAATACGCTGGAGAACTTAACGGTAGAAGCAGCGAC
AGGCGGGAAAACCGTTGACCAGTTAGCACAGTCTTTGCGAGATTTAGTCGATAACCTTATCCCAACTCGCTAA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8008.89 Da        Isoelectric Point: 5.6233

>AT45769 WP_016941532.1 NZ_CP006929:c116782-116561 [Dickeya zeae EC1]
MRTFTSTQARANISAVLDAATQGEPVEITRRDGSSAVVISKADFEAYQNAKLDAEFDVIMQRHGHTVEALTNR

Download         Length: 222 bp

>AT45769 NZ_CP006929:c116782-116561 [Dickeya zeae EC1]
ATGCGTACATTCACCTCAACTCAAGCCCGTGCCAATATCTCAGCAGTATTGGATGCCGCTACTCAAGGTGAACCGGTTGA
AATCACTCGTAGAGATGGCAGTTCAGCGGTGGTTATCAGCAAGGCTGACTTCGAGGCATACCAAAACGCTAAACTCGATG
CCGAGTTTGATGTGATTATGCAGCGTCATGGACACACCGTAGAGGCACTGACAAACCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References