Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1993974..1994119 Replicon chromosome
Accession NZ_CP006923
Organism Klebsiella pneumoniae 30660/NJST258_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1994010..1994112 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1993974..1994119 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KPNJ1_RS09965 1989104..1991164 + 2061 WP_004151449.1 oligopeptidase B -
KPNJ1_RS09970 1991168..1991827 - 660 WP_002911407.1 exodeoxyribonuclease X -
KPNJ1_RS09975 1991906..1992136 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KPNJ1_RS09980 1992249..1992623 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KPNJ1_RS09985 1992627..1993496 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KPNJ1_RS09990 1993513..1993851 + 339 WP_002911404.1 YebY family protein -
- 1993974..1994119 - 146 - - Antitoxin
- 1994010..1994112 + 103 - - Toxin
KPNJ1_RS30380 1994487..1994630 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KPNJ1_RS10000 1994735..1995703 - 969 WP_004151446.1 VirK/YbjX family protein -
KPNJ1_RS10005 1995860..1996513 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
KPNJ1_RS10010 1996510..1996701 - 192 WP_002911395.1 YebW family protein -
KPNJ1_RS10015 1996799..1997038 - 240 WP_002911393.1 YebV family protein -
KPNJ1_RS10020 1997154..1998587 - 1434 WP_025403962.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T45753 NZ_CP006923:1994010-1994112 [Klebsiella pneumoniae 30660/NJST258_1]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT45753 NZ_CP006923:c1994119-1993974 [Klebsiella pneumoniae 30660/NJST258_1]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References