Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1995299..1995444 Replicon chromosome
Accession NZ_CP006918
Organism Klebsiella pneumoniae 30684/NJST258_2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1995335..1995437 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1995299..1995444 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KPNJ2_RS09915 1990429..1992489 + 2061 WP_004151449.1 oligopeptidase B -
KPNJ2_RS09920 1992493..1993152 - 660 WP_002911407.1 exodeoxyribonuclease X -
KPNJ2_RS09925 1993231..1993461 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KPNJ2_RS09930 1993574..1993948 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KPNJ2_RS09935 1993952..1994821 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KPNJ2_RS09940 1994838..1995176 + 339 WP_002911404.1 YebY family protein -
- 1995299..1995444 - 146 - - Antitoxin
- 1995335..1995437 + 103 - - Toxin
KPNJ2_RS29075 1995812..1995955 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KPNJ2_RS09950 1996060..1997028 - 969 WP_004151446.1 VirK/YbjX family protein -
KPNJ2_RS09955 1997185..1997838 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
KPNJ2_RS09960 1997835..1998026 - 192 WP_002911395.1 YebW family protein -
KPNJ2_RS09965 1998124..1998363 - 240 WP_002911393.1 YebV family protein -
KPNJ2_RS09970 1998479..1999912 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T45734 NZ_CP006918:1995335-1995437 [Klebsiella pneumoniae 30684/NJST258_2]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT45734 NZ_CP006918:c1995444-1995299 [Klebsiella pneumoniae 30684/NJST258_2]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References