Detailed information of TA system TA045722

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-dinJ/YafQ-RelB
• Location: 3250145..3250751
• Replicon: chromosome
• Accession: NZ_CP006877
• Organism: Rhizobium gallicum bv. gallicum R602

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: RGR602_RS35740
• Protein ID: WP_100674343.1
• Coordinates: 3250145..3250480 (-)
• Length: 112 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: A0A0B4X341
• Locus tag: RGR602_RS15940
• Protein ID: WP_039846953.1
• Coordinates: 3250470..3250751 (-)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RGR602_RS15920	3245444..3246526	+	1083	WP_039845900.1	4-oxalomesaconate tautomerase	-
RGR602_RS15925	3246572..3247573	+	1002	WP_039845901.1	ABC transporter substrate-binding protein	-
RGR602_RS15930	3247649..3248419	+	771	WP_203226204.1	ABC transporter ATP-binding protein	-
RGR602_RS15935	3248403..3249179	+	777	WP_039845903.1	ABC transporter permease	-
RGR602_RS35740	3250145..3250480	-	336	WP_100674343.1	type II toxin-antitoxin system YafQ family toxin	Toxin
RGR602_RS15940	3250470..3250751	-	282	WP_039846953.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
RGR602_RS37240	3251148..3251678	+	531	WP_052451598.1	hypothetical protein	-
RGR602_RS37245	3251675..3252019	+	345	WP_052451599.1	transposase	-
RGR602_RS15955	3252673..3253623	+	951	WP_039845905.1	AraC family transcriptional regulator	-
RGR602_RS15960	3254044..3254874	+	831	WP_039845906.1	alpha/beta hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (21-111)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (4-72)

Sequences

Toxin

Protein

• Length: 112 a.a.
• Molecular weight: 12609.30 Da
• Isoelectric Point: 8.9718

>T45722 WP_100674343.1 NZ_CP006877:c3250480-3250145 [Rhizobium gallicum bv. gallicum R602]
MSSDKKRAKSASSKRASLPRQSSHTKQFQKDWERLSRSGRYDMVALKKVVGLIVDNDGPLPAELKDHELTGDWKDHRECH
IGGDFLLIYTLDERKNLVVFVAAGTHAELFE

Nucleotide

• Length: 336 bp

>T45722 NZ_CP006877:c3250480-3250145 [Rhizobium gallicum bv. gallicum R602]
TTGTCAAGTGATAAGAAACGAGCGAAGTCCGCTTCCAGCAAGCGGGCTTCGCTGCCGCGGCAATCAAGTCATACCAAACA
GTTTCAAAAAGATTGGGAGCGCCTTTCTAGGTCTGGCCGATATGATATGGTCGCACTGAAGAAAGTCGTGGGTTTGATCG
TAGACAACGATGGCCCTCTGCCGGCGGAACTGAAAGACCACGAGCTGACGGGTGATTGGAAAGATCATCGAGAATGTCAT
ATCGGCGGTGATTTTCTCCTCATCTACACGTTAGACGAAAGAAAGAACCTGGTTGTGTTCGTAGCCGCTGGGACACACGC
CGAACTCTTTGAATGA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10131.75 Da
• Isoelectric Point: 9.8103

>AT45722 WP_039846953.1 NZ_CP006877:c3250751-3250470 [Rhizobium gallicum bv. gallicum R602]
MAANAYVRARIEPSVKDSAALVLDSLGLTTSDIIRIVLTRIARDKALPVELTRPNAKTIAAMEEARAIKAGHGKHFDTAD
EMFESLEGRKVVK

Nucleotide

• Length: 282 bp

>AT45722 NZ_CP006877:c3250751-3250470 [Rhizobium gallicum bv. gallicum R602]
ATGGCTGCAAACGCATATGTACGCGCCCGCATTGAACCTTCGGTGAAGGATAGCGCCGCCTTGGTACTCGATAGTCTCGG
ACTGACCACCTCGGATATCATCCGAATCGTTTTGACCAGGATCGCCCGAGATAAAGCTCTTCCCGTCGAATTGACTCGAC
CGAACGCCAAAACAATCGCTGCGATGGAGGAAGCAAGAGCCATCAAGGCGGGTCACGGCAAGCATTTTGATACTGCTGAT
GAGATGTTTGAGTCACTCGAGGGACGCAAGGTTGTCAAGTGA

Structures

Antitoxin

• AlphaFold DB: A0A0B4X341