Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4700589..4700950 Replicon chromosome
Accession NZ_CP006857
Organism Xanthomonas citri subsp. citri A306

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag J151_RS20690 Protein ID WP_005914328.1
Coordinates 4700589..4700723 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag J151_RS20695 Protein ID WP_003486606.1
Coordinates 4700798..4700950 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J151_RS20670 4695727..4697418 - 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -
J151_RS20675 4697610..4698644 - 1035 WP_011052671.1 MBL fold metallo-hydrolase -
J151_RS20680 4698683..4699972 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
J151_RS20685 4700153..4700362 - 210 WP_003486601.1 CsbD family protein -
J151_RS20690 4700589..4700723 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
J151_RS20695 4700798..4700950 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
J151_RS20700 4701057..4701980 - 924 WP_005927745.1 arginase -
J151_RS20705 4702301..4702753 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
J151_RS20710 4702817..4703176 + 360 WP_003486613.1 hypothetical protein -
J151_RS20715 4703273..4704190 + 918 WP_011052673.1 hypothetical protein -
J151_RS20720 4704187..4704729 + 543 WP_003486615.1 GTPase -
J151_RS20725 4705167..4705850 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T45716 WP_005914328.1 NZ_CP006857:c4700723-4700589 [Xanthomonas citri subsp. citri A306]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T45716 NZ_CP006857:c4700723-4700589 [Xanthomonas citri subsp. citri A306]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT45716 WP_003486606.1 NZ_CP006857:c4700950-4700798 [Xanthomonas citri subsp. citri A306]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT45716 NZ_CP006857:c4700950-4700798 [Xanthomonas citri subsp. citri A306]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References