Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 906859..907429 Replicon chromosome
Accession NZ_CP006823
Organism Helicobacter pylori oki154

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HPOKI154_RS04355 Protein ID WP_025366905.1
Coordinates 906859..907131 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HPOKI154_RS04360 Protein ID WP_025222956.1
Coordinates 907118..907429 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HPOKI154_RS04335 903523..904290 - 768 WP_025222953.1 ABC transporter ATP-binding protein -
HPOKI154_RS04340 904290..905270 - 981 WP_000921481.1 iron ABC transporter permease -
HPOKI154_RS04345 905263..906111 - 849 WP_025366904.1 SDR family oxidoreductase -
HPOKI154_RS04350 906252..906776 + 525 WP_001120215.1 acyl-CoA thioesterase -
HPOKI154_RS04355 906859..907131 - 273 WP_025366905.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
HPOKI154_RS04360 907118..907429 - 312 WP_025222956.1 hypothetical protein Antitoxin
HPOKI154_RS04365 907888..910119 - 2232 WP_025366906.1 Hop family adhesin BabA -
HPOKI154_RS04380 910622..911143 + 522 WP_025313945.1 hypothetical protein -
HPOKI154_RS04385 911094..912206 - 1113 WP_025222959.1 hydrogenase formation protein HypD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10630.69 Da        Isoelectric Point: 9.9378

>T45635 WP_025366905.1 NZ_CP006823:c907131-906859 [Helicobacter pylori oki154]
MLMIETSKKFDKDLKILVKNGFDLKLLYKMVENLAKEQPLDPKYKDHPLKGALKNFRECHLKPDLLLVYQIKKQENTLFL
VRLGSHSELF

Download         Length: 273 bp

>T45635 NZ_CP006823:c907131-906859 [Helicobacter pylori oki154]
ATGCTGATGATTGAAACCAGTAAAAAATTTGATAAGGATCTTAAAATTCTTGTTAAAAACGGGTTTGATTTAAAGCTTTT
ATATAAAATGGTTGAAAATTTAGCCAAAGAGCAACCCCTAGATCCCAAATACAAAGACCACCCGCTCAAAGGCGCTTTAA
AAAATTTTAGGGAATGCCACCTAAAACCGGATTTATTGCTTGTCTATCAAATTAAAAAACAAGAAAACACCCTCTTTTTA
GTAAGACTAGGCAGTCATAGCGAGCTGTTTTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12407.22 Da        Isoelectric Point: 10.1678

>AT45635 WP_025222956.1 NZ_CP006823:c907429-907118 [Helicobacter pylori oki154]
MPNSPTKKDYTQYSEKQLFNFLNSIKTKQKRALEKLKEIQTQKQRIKKALQFKTLHLTENGYTIEEEREILSRAKDTKNH
LCFKNIEDFKKHCENLRFKNADD

Download         Length: 312 bp

>AT45635 NZ_CP006823:c907429-907118 [Helicobacter pylori oki154]
ATGCCTAATTCTCCCACCAAAAAAGACTACACACAATACAGCGAAAAACAGCTTTTTAACTTTCTAAATTCTATCAAGAC
CAAACAAAAAAGAGCGTTAGAAAAATTGAAAGAAATCCAAACTCAAAAGCAAAGAATTAAAAAAGCGCTCCAATTTAAAA
CGCTCCATTTAACCGAAAACGGATACACCATAGAAGAAGAGCGAGAAATCTTATCAAGGGCTAAAGACACCAAGAACCAC
CTTTGTTTTAAAAATATAGAGGATTTTAAAAAGCATTGTGAAAACTTAAGATTTAAAAATGCTGATGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References