Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1472234..1472379 Replicon chromosome
Accession NZ_CP006798
Organism Klebsiella pneumoniae subsp. pneumoniae PittNDM01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1472241..1472343 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1472234..1472379 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Q770_RS07285 1467765..1469198 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
Q770_RS07290 1469314..1469553 + 240 WP_002911393.1 YebV family protein -
Q770_RS07295 1469651..1469842 + 192 WP_002911395.1 YebW family protein -
Q770_RS07300 1469839..1470492 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
Q770_RS07305 1470649..1471617 + 969 WP_004151446.1 VirK/YbjX family protein -
Q770_RS31260 1471722..1471865 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1472234..1472379 + 146 - - Antitoxin
- 1472241..1472343 - 103 - - Toxin
Q770_RS07315 1472502..1472840 - 339 WP_002911404.1 YebY family protein -
Q770_RS07320 1472857..1473726 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
Q770_RS07325 1473730..1474104 - 375 WP_004151448.1 CopC domain-containing protein YobA -
Q770_RS07330 1474217..1474447 + 231 WP_002911406.1 DNA polymerase III subunit theta -
Q770_RS07335 1474526..1475185 + 660 WP_043906809.1 exodeoxyribonuclease X -
Q770_RS07340 1475189..1477249 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T45604 NZ_CP006798:c1472343-1472241 [Klebsiella pneumoniae subsp. pneumoniae PittNDM01]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT45604 NZ_CP006798:1472234-1472379 [Klebsiella pneumoniae subsp. pneumoniae PittNDM01]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References