Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1945927..1946072 Replicon chromosome
Accession NZ_CP006738
Organism Klebsiella pneumoniae HK787

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1945963..1946065 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1945927..1946072 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P244_RS09465 1941057..1943117 + 2061 WP_004151449.1 oligopeptidase B -
P244_RS09470 1943121..1943780 - 660 WP_002911407.1 exodeoxyribonuclease X -
P244_RS09475 1943859..1944089 - 231 WP_002911406.1 DNA polymerase III subunit theta -
P244_RS09480 1944202..1944576 + 375 WP_004151448.1 CopC domain-containing protein YobA -
P244_RS09485 1944580..1945449 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
P244_RS09490 1945466..1945804 + 339 WP_002911404.1 YebY family protein -
- 1945927..1946072 - 146 - - Antitoxin
- 1945963..1946065 + 103 - - Toxin
P244_RS27950 1946439..1946582 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
P244_RS09500 1946687..1947655 - 969 WP_004151446.1 VirK/YbjX family protein -
P244_RS09505 1947812..1948465 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
P244_RS09510 1948462..1948653 - 192 WP_002911395.1 YebW family protein -
P244_RS09515 1948751..1948990 - 240 WP_002911393.1 YebV family protein -
P244_RS09520 1949106..1950539 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T45479 NZ_CP006738:1945963-1946065 [Klebsiella pneumoniae HK787]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAGGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT45479 NZ_CP006738:c1946072-1945927 [Klebsiella pneumoniae HK787]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCCTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References