Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2104158..2104303 Replicon chromosome
Accession NZ_CP006722
Organism Klebsiella pneumoniae subsp. pneumoniae 1158

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2104194..2104296 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2104158..2104303 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P243_RS09955 2099288..2101348 + 2061 WP_004151449.1 oligopeptidase B -
P243_RS09960 2101352..2102011 - 660 WP_002911407.1 exodeoxyribonuclease X -
P243_RS09965 2102090..2102320 - 231 WP_002911406.1 DNA polymerase III subunit theta -
P243_RS09970 2102433..2102807 + 375 WP_004151448.1 CopC domain-containing protein YobA -
P243_RS09975 2102811..2103680 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
P243_RS09980 2103697..2104035 + 339 WP_002911404.1 YebY family protein -
- 2104158..2104303 - 146 - - Antitoxin
- 2104194..2104296 + 103 - - Toxin
P243_RS28360 2104671..2104814 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
P243_RS09990 2104919..2105887 - 969 WP_004151446.1 VirK/YbjX family protein -
P243_RS09995 2106044..2106697 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
P243_RS10000 2106694..2106885 - 192 WP_002911395.1 YebW family protein -
P243_RS10005 2106983..2107222 - 240 WP_002911393.1 YebV family protein -
P243_RS10010 2107338..2108771 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T45458 NZ_CP006722:2104194-2104296 [Klebsiella pneumoniae subsp. pneumoniae 1158]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT45458 NZ_CP006722:c2104303-2104158 [Klebsiella pneumoniae subsp. pneumoniae 1158]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References