Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 5814088..5815778 Replicon chromosome
Accession NZ_CP006704
Organism Comamonas testosteroni TK102

Toxin (Protein)


Gene name doc Uniprot ID A0A076Q091
Locus tag O987_RS26385 Protein ID WP_043375747.1
Coordinates 5814900..5815778 (-) Length 293 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID A0A076PRU1
Locus tag O987_RS26380 Protein ID WP_043375746.1
Coordinates 5814088..5814894 (-) Length 269 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(44-277)

Antitoxin

Transcription regulator IclR, C-terminal

(137-257)


Sequences

Toxin        


Download         Length: 293 a.a.        Molecular weight: 30429.89 Da        Isoelectric Point: 6.6025

>T45438 WP_043375747.1 NZ_CP006704:c5815778-5814900 [Comamonas testosteroni TK102]
MHEDLLSPKLQLLQTGFPERLVKLPQNAQVAWREAGDASSDFAVVLLHGISSGAASWLDVALQLGDKARVLAWDAPGYGV
STPLAPAAPADADYAQALAQSLLVLGVRRCLLVGHSLGALMAARLAVTAAPGLVEQLVFISPAGGYGAAAKAEQQAKVRA
GRLAALAEKGVAGLAAVIDQRLVSSEAPEAVRAWVRWNTARMQPQGYAQAVELLCGSDLAQAQGRLGMPVQVWVGEHDVV
TPPAACKAWSELLGAHYGTLAAAGHASPVEQPVEVAHRLASLLNQSYLPNTS

Download         Length: 879 bp

>T45438 NZ_CP006704:c5815778-5814900 [Comamonas testosteroni TK102]
ATGCACGAGGATTTGCTGTCGCCGAAGCTGCAGCTGCTGCAGACCGGATTTCCCGAGCGACTGGTAAAGCTCCCGCAGAA
CGCTCAGGTTGCCTGGCGCGAGGCGGGCGATGCCAGCTCCGATTTTGCGGTGGTGCTGCTGCATGGCATCAGCTCCGGGG
CTGCCTCCTGGCTGGATGTGGCGCTGCAGCTGGGTGACAAGGCGCGCGTTCTGGCCTGGGATGCACCCGGCTATGGCGTG
TCGACGCCGCTGGCGCCAGCCGCGCCTGCCGATGCCGACTATGCGCAGGCGCTGGCCCAGTCACTGCTGGTGCTGGGCGT
GCGGCGCTGTCTGCTGGTCGGCCATTCCCTGGGCGCCCTGATGGCTGCCAGGCTGGCGGTCACGGCGGCCCCCGGACTGG
TCGAGCAACTGGTGTTCATCAGCCCGGCCGGCGGTTACGGCGCAGCGGCCAAGGCCGAGCAGCAAGCCAAGGTGCGCGCA
GGACGTCTGGCTGCGCTGGCCGAGAAAGGTGTCGCCGGCCTGGCGGCCGTCATCGACCAGCGTCTGGTGTCTTCCGAAGC
CCCTGAAGCCGTGCGTGCATGGGTGCGCTGGAATACGGCGCGCATGCAGCCGCAGGGCTATGCGCAGGCGGTCGAGCTGC
TCTGCGGCAGTGATCTGGCGCAGGCACAGGGCAGGCTGGGCATGCCGGTTCAGGTCTGGGTCGGCGAGCACGATGTGGTG
ACTCCGCCTGCAGCTTGCAAAGCCTGGTCCGAGTTGCTGGGCGCGCACTACGGTACGCTTGCGGCTGCCGGTCATGCTTC
ACCCGTGGAACAACCTGTGGAGGTTGCGCATAGGCTGGCATCTTTGTTGAACCAAAGTTATTTGCCCAACACCAGCTGA

Antitoxin


Download         Length: 269 a.a.        Molecular weight: 29265.23 Da        Isoelectric Point: 4.8865

>AT45438 WP_043375746.1 NZ_CP006704:c5814894-5814088 [Comamonas testosteroni TK102]
MSETPEISTNDQDRYTVPALERGLRLLACFGPEQPVWSAPELARNLELPRSTVFRMLTTLENSGYLQRSGTEYRLGLAVL
RLGYDYLSTQPLAQLAEPALQALCDELGMTSNLALRDGASVVYVARVTPAGAFQGAVRVGSRLPAHATVLGRALLHDMDA
AQLRSVFGGEELPQFSESTPRNIDELLDLLAQDRERGYAMGEGFYEPGVSSIAAPVRAADGRVVAGLAMAIPFTELVPEK
TQLWVQKVQEAAEALSAHLRQQHPDHLR

Download         Length: 807 bp

>AT45438 NZ_CP006704:c5814894-5814088 [Comamonas testosteroni TK102]
ATGAGCGAAACCCCAGAGATTTCAACCAACGACCAAGACCGTTACACCGTGCCCGCCCTCGAGCGAGGACTGCGCCTGCT
GGCCTGCTTTGGCCCGGAGCAACCTGTCTGGAGCGCGCCCGAGCTGGCGCGCAACCTCGAGCTGCCGCGTTCCACGGTGT
TTCGGATGTTGACCACGCTTGAAAACTCGGGGTATCTGCAGCGCAGCGGTACCGAATACCGACTCGGTCTGGCCGTGCTG
CGTCTGGGCTACGACTACCTGTCCACCCAGCCGCTGGCGCAACTGGCCGAGCCTGCTCTGCAGGCCTTGTGTGATGAGCT
GGGCATGACCAGCAATCTTGCATTGCGTGACGGCGCCTCCGTGGTCTATGTGGCACGCGTCACTCCGGCCGGAGCGTTCC
AGGGCGCTGTGCGCGTGGGCTCGCGCTTGCCTGCACATGCGACGGTGCTGGGGCGAGCCCTGCTGCATGACATGGATGCC
GCGCAACTGCGCTCGGTGTTTGGCGGCGAGGAATTGCCCCAGTTCTCCGAGAGCACGCCGCGCAACATCGACGAGCTGCT
GGACCTGCTGGCCCAGGACCGTGAGCGTGGCTACGCCATGGGCGAGGGCTTTTACGAGCCAGGTGTTTCCAGTATTGCAG
CGCCGGTGCGCGCCGCAGACGGGCGGGTGGTTGCGGGACTGGCCATGGCCATTCCGTTTACCGAGCTGGTGCCCGAGAAA
ACCCAGCTCTGGGTGCAGAAGGTGCAAGAGGCGGCAGAAGCCCTGTCCGCTCATTTGCGCCAGCAGCACCCGGACCATTT
GCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A076Q091

Antitoxin

Source ID Structure
AlphaFold DB A0A076PRU1

References